An In Vitro Experimental Evaluation of the Displacement Field in an Intracranial Aneurysm Model

  • Diana PinhoEmail author
  • David Bento
  • João Ribeiro
  • Rui Lima
  • Mário Vaz
Conference paper
Part of the Mechanisms and Machine Science book series (Mechan. Machine Science, volume 24)


The purpose of this paper is to develop a system able to study experimentally the displacement field of an in vitro intracranial aneurysm. Origin and growth of aneurysms is the result of a complex interaction between biological processes in the arterial wall and the involved hemodynamic phenomena’s. Once the aneurysm forms, the repetitive pressure and shear stresses exerted by the blood flow on the debilitated arterial wall can cause a gradual expansion. One promising method to evaluate and measure this expansion is to use optical field experimental techniques, such as interferometry. In this work the Electronic Speckle Pattern Interferometry was used to evaluate the deformation occurred on an intracranial aneurysm model fabricated in polydimensiloxane (PDMS) by using a 3D printer combined with a soft lithography technique.


Aneurysms Displacement field Electronic speckle pattern interferometry 3D printer In Vitro models 



The authors acknowledge the financial support provided by PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/2215/2013, scholarship SFRH/BD/91192/2012 and scholarship SFRH/BD/89077/2012 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER).


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Diana Pinho
    • 1
    Email author
  • David Bento
    • 1
  • João Ribeiro
    • 1
  • Rui Lima
    • 2
  • Mário Vaz
    • 3
  1. 1.Polytechnic Institute of BragançaUniversity of PortoPortoPortugal
  2. 2.Polytechnic Institute of Bragança/CEFT, FEUPUniversity of PortoPortoPortugal
  3. 3.University of PortoPortoPortugal

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