Clear Cell Carcinoma

  • Joaquín J. García


Clear cell carcinoma affects primarily adults and presents at a mean age of approximately 60 years. Women are involved more than men. The majority of cases involve minor salivary glands in the oral cavity, presenting as single or multiple masses. Most cases of clear cell carcinoma behave as low-grade malignancies. Clear cell carcinoma is infiltrative, comprised of one cell type (ductal), and may exhibit a variety of architectural patterns (single cells, nests, trabeculae, and solid) with or without hyalinized stroma (Figs. 12.1, 12.2, 12.3, 12.4, 12.5, 12.6, 12.7, 12.8, 12.9, 12.10, 12.11, 12.12, 12.13, 12.14, 12.15, 12.16, 12.17, 12.18, 12.19 and 12.20).


Clear cell adenocarcinoma Hyalinizing clear cell carcinoma 

Suggested Reading

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Joaquín J. García
    • 1
  1. 1.Mayo Clinic School of Medicine, Department of Laboratory Medicine & PathologyMayo Clinic RochesterRochesterUSA

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