Advertisement

Carcinosarcoma

  • Joaquín J. García
Chapter

Abstract

Carcinosarcoma is an exceedingly rare malignancy that affects adults and presents at a mean age of approximately 60 years. Women are involved less than men. The majority of cases involve major salivary glands, presenting as single or multiple masses. Most cases of carcinosarcoma behave as high-grade malignancies. Carcinosarcoma is infiltrative and comprised of carcinomatous and heterologous sarcomatous elements (Figs. 11.1, 11.2, 11.3, 11.4, 11.5, 11.6, 11.7, 11.8, 11.9, 11.10, 11.11, 11.12, 11.13, 11.14, 11.15, 11.16, 11.17 and 11.18).

Keywords

True malignant mixed tumor Sarcomatoid carcinoma 

Suggested Reading

  1. Alvarez-Cañas C, Rodilla IG. True malignant mixed tumor (carcinosarcoma) of the parotid gland. Report of a case with immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;81:454–8.CrossRefGoogle Scholar
  2. Bhalla RK, Jones TM, Taylor W, Roland NJ. Carcinosarcoma (malignant mixed tumor) of the submandibular gland: a case report and review of the literature. J Oral Maxillofac Surg. 2002;60(9):1067–9.CrossRefGoogle Scholar
  3. Götte K, Riedel F, Coy JF, Spahn V, Hörmann K. Salivary gland carcinosarcoma: immunohistochemical, molecular genetic and electron microscopic findings. Oral Oncol. 2000;36(4):360–4.CrossRefGoogle Scholar
  4. Gnepp DR. Malignant mixed tumors of the salivary glands: a review. Pathol Annu. 1993;28:279–328.PubMedGoogle Scholar
  5. Harada H. Histomorphological investigation regarding to malignant transformation of pleomorphic adenoma (so-called malignant mixed tumor) of the salivary gland origin; special reference to carcinosarcoma. Kurume Med J. 2000;47:307–23.CrossRefGoogle Scholar
  6. Kwon MY, Gu M. True malignant mixed tumor (carcinosarcoma) of parotid gland with unusual mesenchymal component: a case report and review of the literature. Arch Pathol Lab Med. 2001;125(6):812–5.PubMedGoogle Scholar
  7. Stephen J, Batsakis JG, Luna MA, von der Heyden U, Byers RM. True malignant mixed tumors (carcinosarcoma) of salivary glands. Oral Surg Oral Med Oral Pathol. 1986;61:597–602.CrossRefGoogle Scholar
  8. Taki NH, Laver N, Quinto T, Wein RO. Carcinosarcoma de novo of the parotid gland: case report. Head Neck. 2013;35:E161–3.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2019

Authors and Affiliations

  • Joaquín J. García
    • 1
  1. 1.Mayo Clinic School of Medicine, Department of Laboratory Medicine & PathologyMayo Clinic RochesterRochesterUSA

Personalised recommendations