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Is Volumetric Breast Density Related to Body Mass Index, Body Fat Mass, Waist-Hip Ratio, Age and Ethnicity for Malaysian Women?

  • Norhasnah Zakariyah
  • Kwan-Hoong Ng
  • Susie Lau
  • Kartini Rahmat
  • Farhana Fadzli
  • Nur Aishah Mohd Taib
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8539)

Abstract

Previous studies have shown that breast cancer has been linked to breast density as well as obesity. We aim to investigate the relationships between body mass index (BMI), body fat mass (BFM), waist-hip ratio (WHR), age and ethnicity with volumetric breast density (VBD) among Malaysian women. In this context, VBD is defined as the ratio of fibroglandular tissue volume to total breast volume. We collected anthropomorphic and body composition data for 2457 subjects undergoing mammographic examination at the University of Malaya Medical Centre, Kuala Lumpur. The data included weight, height, BMI and BFM which were measured with a body composition analyzer. We also measured waist and hip circumferences for 500 of these subjects. A VBD assessment system (Volpara) was used to analyze mammograms. Our results showed that VBD is not significantly correlated with BMI (r2 = 0.17), BFM (r2 = 0.19), WHR (r2 = 0.11). We also noted that VBD is highest among Malaysian women below 40 years old. VBD is highest for Chinese (mean = 11.3%), followed by Malay (mean = 10.1%) and Indian (mean = 9.4%). In conclusion, VBD is dependent on age and ethnicity (ANOVA, p<0.05) but not on BMI, BFM and WHR.

Keywords

Body fat mass body mass index breast cancer volumetric breast density mammography obesity waist-hip ratio 

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Norhasnah Zakariyah
    • 1
  • Kwan-Hoong Ng
    • 1
  • Susie Lau
    • 1
  • Kartini Rahmat
    • 1
  • Farhana Fadzli
    • 1
  • Nur Aishah Mohd Taib
    • 2
  1. 1.Department of Biomedical Imaging and University of Malaya Research Imaging Centre, Faculty of MedicineUniversity of MalayaKuala LumpurMalaysia
  2. 2.Department of Surgery, Faculty of MedicineUniversity of MalayaKuala LumpurMalaysia

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