Neurovascular Events After Subarachnoid Hemorrhage pp 183-186

Part of the Acta Neurochirurgica Supplement book series (NEUROCHIRURGICA, volume 120) | Cite as

Real-Time Changes in Brain Tissue Oxygen During Endovascular Treatment of Cerebral Vasospasm

  • Rune Rasmussen
  • Søren Bache
  • Trine Stavngaard
  • Jane Skjøth-Rasmussen
  • Bertil Romner


The use of endovascular intervention to treat cerebral vasospasm after subarachnoid hemorrhage has increased. Although the effect on angiographic vasospasm can be easily demonstrated, the effect on cerebral blood flow and clinical outcome is still controversial. In this report, we investigate minute-by-minute changes in brain tissue oxygen during balloon angioplasty and intraarterial administration of vasodilators in three patients.

Our results confirm that endovascular intervention is capable of not only resolving angiographic vasospasm, but also of normalizing values of brain tissue oxygen pressure (PtiO2) in target parenchyma. However, during the intervention, dangerously low levels of brain tissue oxygen, leading to cerebral infarction, may occur. Thus, no clinical improvement was seen in two of the patients and a dramatic worsening was observed in the third patient. Because the decrease in brain tissue oxygen was seen after administration of vasopressor agents, this may be a contributing factor.


Subarachnoid hemorrhage Cerebral vasospasm Endovascular intervention Brain tissue oxygen monitoring 


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Rune Rasmussen
    • 1
  • Søren Bache
    • 2
  • Trine Stavngaard
    • 3
  • Jane Skjøth-Rasmussen
    • 1
  • Bertil Romner
    • 1
  1. 1.Department of NeurosurgeryCopenhagen University HospitalCopenhagenDenmark
  2. 2.Department of NeuroanesthesiologyCopenhagen University HospitalCopenhagenDenmark
  3. 3.Department of RadiologyCopenhagen University HospitalCopenhagenDenmark

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