Organization of a Weaning Unit

  • Enrico M. Clini
  • Gloria Montanari
  • Laura Ciobanu
  • Michele Vitacca

Abstract

Weaning from mechanical ventilation (MV) is an essential and universal element in the care of critically ill patients receiving MV for a prolonged time to restore unassisted breathing. There is much evidence that weaning tends to be delayed, exposing the patient to unnecessary discomfort, increased risk of complications, and increased cost of care. In the past 15 years, availability of beds in intensive care units (ICUs) and new technologies, such as noninvasive mechanical ventilation, coupled with improved levels of care, have highlighted a new population of patients labeled as survivors of a catastrophic illness. Although this group of patients represents less than 10 % of all ICU admissions, they account for a disproportionate burden on health-care financial resources. In most studies, weaning failure occurs when a spontaneous breathing trial (SBT) fails and reintubation is needed [1]. Failure of an SBT is defined by (1) objective indices of failure, such as tachypnea, tachycardia, hypertension, hypotension, hypoxemia or acidosis, and arrhythmia, and (2) subjective indices, such as agitation or distress, depressed mental status, diaphoresis, and evidence of increasing effort. Several studies have proposed the use of noninvasive ventilation (NIV) for extubated patients in different clinical situations, including prophylactic intervention in patients with chronic obstructive pulmonary disease who failed SBT [2], patients with repeated SBT failure [3], and postsurgical patients.

Keywords

Chronic Obstructive Pulmonary Disease Mechanical Ventilation Prolonged Mechanical Ventilation Spontaneous Breathing Trial Catastrophic Illness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

CINMA

Critical illness neuromuscular abnormalities

CVFs

Chronic ventilator facilities

ICU

Intensive care units

MV

Mechanical ventilation

NIV

Noninvasive ventilation

PMV

Prolonged mechanical ventilation

SWUs

Specialized weaning units

SBT

Spontaneous breathing trial

References

  1. 1.
    Esteban A, Frutos F, Tobin MJ, et al. A comparison of four methods of weaning patients from mechanical ventilation. Spanish Lung Failure Collaborative Group. N Engl J Med. 1995;332:345–50.PubMedCrossRefGoogle Scholar
  2. 2.
    Vitacca M, Vianello A, Colombo D, et al. Comparison of two methods for weaning patients with chronic obstructive pulmonary disease requiring mechanical ventilation for more than 15 days. Am J Respir Crit Care Med. 2001;164:225–30.PubMedCrossRefGoogle Scholar
  3. 3.
    Ferrer M, Esqinas A, Arancibia F, et al. Noninvasive ventilation during persistent weaning failure. Am J Respir Crit Care Med. 2003;168:70–6.PubMedCrossRefGoogle Scholar
  4. 4.
    Brochard L (2005) Pressure support is the preferred weaning method. As presented at the 5th international consensus conference in intensive care medicine: weaning from mechanical ventilation. Hosted by ERS, ATS, ESICM, SCCMand SRLF, Budapest, 28–29 Apr 2005.Google Scholar
  5. 5.
    Boles JM, Bion J, Connors A, et al. Weaning from mechanical ventilation Statement of the Sixth International Consensus Conference on Intensive Care Medicine. Eur Respir J. 2007;29:1033–56.PubMedCrossRefGoogle Scholar
  6. 6.
    Funk GC, Anders S, Breyer MK, et al. Incidence and outcome of weaning from mechanical ventilation according to new categories. Eur Respir J. 2010;35(1):88–94.PubMedCrossRefGoogle Scholar
  7. 7.
    Burtin C, Clerckx B, Robbeets C, et al. Early exercise in critically ill patients enhances short-term functional recovery. Crit Care Med. 2009;37:2499–505.PubMedCrossRefGoogle Scholar
  8. 8.
    Nava S, Vitacca M. Chronic ventilator facilities. In: JTobin M, editor. Principles and practice of mechanical ventilation. 3rd ed. New York: McGraw-Hill; 2013. p. 777–92.Google Scholar
  9. 9.
    Epstein SK, Ciubotaru RL, Wong JB. Effect of failed extubation on the outcome of mechanical ventilation. Chest. 1997;112(1):186–92.PubMedCrossRefGoogle Scholar
  10. 10.
    Seneff MG, Wagner D, Thompson D, et al. The impact of long-term acute-care facilities on the outcome and cost of care for patients undergoing prolonged mechanical ventilation. Crit Care Med. 2000;28:342–50.PubMedCrossRefGoogle Scholar
  11. 11.
    Vitacca M, Clini E, Nava S, et al. High complexity rehabilitation in prolonged weaning patient: role of pneumologist. Rass Patol App Respir. 2013;28:179–87.Google Scholar
  12. 12.
    Nelson JE, Cox CE, Hope AA, et al. Chronic critical illness. Am J Respir Care Med. 2010;182:446–54.CrossRefGoogle Scholar
  13. 13.
    Nelson JE, Meier DE, Litke A, et al. The symptom burden of chronic critical illness. Crit Care Med. 2004;32:1527–34.PubMedCrossRefGoogle Scholar
  14. 14.
    Kahn JM, Benson NM, Appleby D, et al. Long-term acute care hospital utilization after critical illness. JAMA. 2010;303(22):2253–9.PubMedPubMedCentralCrossRefGoogle Scholar
  15. 15.
    Vitacca M, Nava S. Incomplete network for survivors of catastrophic illness after release from ICUs. Respir Care. 2013;58(2):384–5.CrossRefGoogle Scholar
  16. 16.
    Kahn JM. The evolving role of dedicated weaning facilities in critical care. Intensive Care Med. 2010;36:8–10.PubMedCrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Enrico M. Clini
    • 1
  • Gloria Montanari
    • 1
  • Laura Ciobanu
    • 2
  • Michele Vitacca
    • 3
  1. 1.Department of Medical and Surgical Sciences, AOU PoliclinicoUniversity of Modena Reggio EmiliaModenaItaly
  2. 2.Clinical Hospital of RehabilitationUniversity of Medicine and Pharmacy “Gr T Popa”IasiRomania
  3. 3.Fondazione Maugeri IRCCSRehabilitation Centre, Pneumology UnitLumezzane (BS)Italy

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