System Dynamics and Agent-Based Simulation for Prospective Health Technology Assessments

  • Anatoli DjanatlievEmail author
  • Peter Kolominsky-Rabas
  • Bernd M. Hofmann
  • Axel Aisenbrey
  • Reinhard German
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 256)


Healthcare innovations open new treatment possibilities for patients and offer potentials to increase their life quality. But it is also possible that a new product will have negative influences on patient’s life quality, if it has not been checked before. To prevent latter cases three already established methods can be used in order to assess healthcare technologies and to inform regulatory agencies. But these tools share a common problem. They can only be applied when a product is already developed and high costs have been already produced. This work describes Prospective Health Technology Assessment. This approach uses hybrid simulation techniques in order to learn about the impacts of a new innovation before a product has been developed. System Dynamics is used to perform high-level simulation and Agent-Based Simulation allows to model individual behavior of persons.


Healthcare Simulation Hybrid Simulation System Dynamics Agent-based Simulation Prospective Health Technology Assessment Ischemic Stroke 


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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Anatoli Djanatliev
    • 1
    Email author
  • Peter Kolominsky-Rabas
    • 2
  • Bernd M. Hofmann
    • 3
  • Axel Aisenbrey
    • 3
  • Reinhard German
    • 1
  1. 1.Department of Computer Science 7University of Erlangen-NurembergErlangen-NurembergGermany
  2. 2.Interdisciplinary Centre for Public HealthUniversity of Erlangen-NurembergErlangen-NurembergGermany
  3. 3.Healthcare SectorSiemens AGErlangenGermany

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