A Non-invasive Assessment of Intracranial Volume Reserve by Measuring Cerebrospinal Fluid Volume with the Aid of CT Imaging

  • Mariusz Glowacki
  • Karol Budohoski
  • Piotr Marszalek
  • Jerzy Walecki
  • Zbigniew Czernicki
Conference paper
Part of the Acta Neurochirurgica Supplementum book series (NEUROCHIRURGICA, volume 106)

Abstract

Introduction

Monitoring changes in the intracranial volume (ICV) reserve and intracranial pressure (ICP) is one of the key issues in the treatment of intracranial pathologies. The aim of this study is to develop a method of monitoring the ICV reserve by analyzing CSF volume measured using CT in specific regions.

Materials and Methods

A total of 20 patients with cerebral injury were evaluated. Analysis was performed using imaging software. On selected scans (three at the basal cistern level and three at the pineal level), the following regions were analyzed: total cerebral surface (TC1, TC2) and bilateral ambient cistern (AC) only at the basal cistern level for cerebrospinal fluid (CSF) volume. Results were correlated with patients’ Glasgow Coma Scale (GCS) scores.

Results

An increase of CSF volume was observed with an improvement in the GCS. From the examined regions, only AC volume showed a statistically significant linear correlation (p < 0.0005) with GCS. Mean AC: 0.021, 0.454, and 0.678 mL CSF/scan in severe (3–8 pts GCS), moderate (9–12 pts GCS), and mild (13–15 pts GCS) TBI groups, respectively.

Discussion

Assessment of CSF volume changes in mL CSF/scan can be conducted using CT. Counting voxels corresponding to the CSF eliminates mistakes due to inaccurate region demarcation. The obtained results (AC volume) show a high correlation with patient state.

Keywords

Intracranial pressure intracranial volume reserve traumatic brain injury non-invasive ICP monitoring voxel 

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Copyright information

© Springer-Verlag/Wien 2010

Authors and Affiliations

  • Mariusz Glowacki
    • 1
  • Karol Budohoski
    • 3
    • 4
  • Piotr Marszalek
    • 1
  • Jerzy Walecki
    • 2
  • Zbigniew Czernicki
    • 3
    • 4
  1. 1.Department of NeurosurgeryM. Mossakowski Medical Research Center, Polish Academy of SciencesWarsawPoland
  2. 2.Department of Radiology and Department of Experimental PharmacologyPolish Academy of Sciences Medical Research CenterWarsawPoland
  3. 3.Department of NeurosurgeryM. Mossakowski Medical Research Center, Polish Academy of SciencesWarsawPoland
  4. 4.Department of Neursourgery, Medical Research Center, Polish Academy of Sciences and Department of NeurosurgeryMedical University of WarsawWarsawPoland

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