Therapeutic potential of computer to cerebral cortex implantable devices
In this article, an overview of some of the latest developments in the field of cerebral cortex to computer interfacing (CCCI) is given. This is posed in the more general context of Brain-Computer Interfaces in order to assess advantages and disadvantages. The emphasis is clearly placed on practical studies that have been undertaken and reported on, as opposed to those speculated, simulated or proposed as future projects. Related areas are discussed briefly only in the context of their contribution to the studies being undertaken. The area of focus is notably the use of invasive implant technology, where a connection is made directly with the cerebral cortex and/or nervous system. Tests and experimentation which do not involve human subjects are invariably carried out a priori to indicate the eventual possibilities before human subjects are themselves involved. Some of the more pertinent animal studies from this area are discussed. The paper goes on to describe human experimentation, in which neural implants have linked the human nervous system bidirectionally with technology and the internet. A view is taken as to the prospects for the future for CCCI, in terms of its broad therapeutic role.
KeywordsNeuromodulation brain-computer interface biological systems implant technology feedback control
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- 6.Donoghue J, Nurmikko A, Friehs G, Black M (2004) Development of a neuromotor prosthesis for humans. Chapter 63 in advances in clinical neurophysiology. Clin Neurophysiol Suppl 57: 588–602Google Scholar
- 7.Finn W, LoPresti P (eds) (2003) Handbook of Neuroprosthetic methods. CRC PressGoogle Scholar
- 9.Gasson M, Hutt B, Goodhew I, Kyberd P, Warwick K (2005) Invasive neural prosthesis for neural signal detection and nerve stimulation. Proc Inter J Adapt Contr Sign Proc 19: 365–375Google Scholar
- 10.Gasson M, Yung S, Aziz T, Stein J, Warwick K (2005) Towards a demand driven deep brain stimulator for the treatment of movement disorders. Proc. 3rd IEE International Seminar on Medical Applications of Signal Processing, pp 16/1–16/4Google Scholar
- 11.Grill W, Kirsch R (2000) Neuroprosthetic applications of electrical stimulation. Assis Techn 12: 6–16Google Scholar
- 20.Rizzo J, Wyatt J, Humayun M, DeJuan E, Liu W, Chow A, Eckmiller R, Zrenner E, Yagi T, Abrams G (2001) Retinal prosthesis: an encouraging first decade with major challenges ahead. Opthalmology 108, No 1Google Scholar
- 22.Warwick K (2004) I Cyborg, University of Illinois PressGoogle Scholar
- 25.Warwick K, Gasson M, Hutt B, Goodhew I (2005) An attempt to extend human sensory capabilities by means of implant technology. Proc. IEEE Int. Conference on Systems, Man and Cybernetics, Hawaii, pp 1663–1668Google Scholar
- 26.Wolpaw J, McFarland D, Neat G, Forheris C (1990) An EEG based brain-computer interface for cursor control. Electroencephalogr Clin Neurophysiol 78: 252–259Google Scholar
- 27.Xie S, Yang Z, Yang Y (2004) Brain-computer interface based on event-related potentials during imitated natural reading, Inter J Psychol Suppl 39: S138Google Scholar
- 29.Yu N, Chen J, Ju M (2001) Closed-loop control of quadriceps/hamstring activation for FES-induced standing-up movement of paraplegics. J Musculoskel Res 5: 173–184Google Scholar