On Selected Individual-based Approaches to the Dynamics in Multicellular Systems

  • Dirk Drasdo
Part of the Mathematics and Biosciences in Interaction book series (MBI)


In recent years a number of different individual-based models for spatiotemporal dynamics in multicellular organisms or parts of them have been established. Individual-based models (here: individuum = cell) become necessary if (i) one is interested in understanding the organization principles in tissues down to length scales of the order of a cell diameter in order to link the microscopic dynamics with a collective phenomenon, and (ii) the phenomenon under study includes variations of material or kinetic properties on length scales of the order of the cell diameter. In this article we give a brief overview over a number of individual-based model approaches.


Cellular Automaton Voronoi Diagram Voronoi Cell Voronoi Tessellation Intestinal Crypt 
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Authors and Affiliations

  • Dirk Drasdo
    • 1
  1. 1.Max-Planck-Institute for Mathematics in the ScienceLeipzigGermany

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