Xylitol in dietetics and medicine

  • Kauko K. Mäkinen
Part of the Experientia Supplementum book series (EXS, volume 30)


The detection of L-xylulose in the urine of non-pentosuric humans [250–252], guinea-pigs [251] and rats [252] indicated that this ketopentose may be a normal metabolite in mammals. This idea was supported by the discovery of a very active enzyme system for the reduction of L-xylulose to xylitol [253]. It was also found that D-xylulose 5-phosphate, rather than Dribulose 5-phosphate, is the ketopentose substrate of transketolase in the 6phosphogluconate pathway [254, 255]. Simultaneously, new mitochondrial enzymes linking metabolically the two enantiomorphic forms of xylulose were studied in guinea-pig liver [249].


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Copyright information

© Springer Basel AG 1978

Authors and Affiliations

  • Kauko K. Mäkinen
    • 1
  1. 1.Institute of DentistryUniversity of TurkuTurkuFinland

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