Abstract
The understanding of the role of dysregulated tyrosine kinases in cancer has produced a literal explosion in approaches to cancer treatment.
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Paul MK, Mukhopadhyay AK. Tyrosine kinase—role and significance in cancer. Int J Med Sci. 2004;1(2):101–115. https://doi.org/10.7150/ijms.1.101. PMID: 15912202; PMCID: PMC1074718.
Cheng H, Force T. Why do kinase inhibitors cause cardiotoxicity and what can be done about it? Prog Cardiovasc Dis. 2010;53(2):114–20. https://doi.org/10.1016/j.pcad.2010.06.006. PMID: 20728698.
Chang HM, Moudgil R, Scarabelli T, Okwuosa TM, Yeh ETH. Cardiovascular complications of cancer therapy: best practices in diagnosis, prevention, and management: part 1. J Am Coll Cardiol. 2017;70(20):2536–51. https://doi.org/10.1016/j.jacc.2017.09.1096.
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. Cancer J Clin. 2020;70(1):7. PMID: 31912902.
Casali P.G., Abecasis N, Bauer S., et al. Soft tissue and visceral sarcomas: ESM-EURACA clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29(4):iv51–iv67. https://doi.org/10.1093/annonc/mdy096.
Krieg AH, Hefti F, Speth BM, et al. Synovial sarcomas usually metastasize after >5 years: a multicenter retrospective analysis with minimum follow-up of 10 years for survivors. Ann Oncol. 2011;22(458). PMID: 20716627.
Rothermundt C, Whelan JS, Dileo P, et al. What is the role of routine follow-up for localized limb soft tissue sarcomas? A retrospective analysis of 174 patients. Br J Cancer. 2014;110(2420). PMID: 24736584.
Votrient [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2017. https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/votrient.pdf. Accessed 19 Aug 2017.
Pinkhas D., Ho T., Smith S. Assessment of pazopanib-related hypertension, cardiac dysfunction and identification of clinical risk factors for their development. Cardiooncology. 2017;3(5). MCID: PMC5828231. https://doi.org/10.1186/s40959-017-0024-8.
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Echocardiogram parasternal long axis view demonstrating fluctuating mass in the right atrium (mediastinal tumor ingrowth) and mild diffuse hypokinesis of the left ventricle (PPTX 1708 kb)
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Dundua, D.P., Kedrova, A.G., Plokhova, E.V., Zvezdkina, E.A., Drobiazko, O.A. (2021). Introduction to Tyrosine Kinase Inhibitors: Pazopanib Cardiotoxicity. In: Steingart, R.M., Liu, J.E. (eds) Atlas of Imaging in Cardio-Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-70998-3_5
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