Skip to main content

How Are You Feeling? Symptoms of Kidney Disease

  • Chapter
  • First Online:
Understanding Kidney Diseases

Abstract

In this chapter we explain:

  • Symptoms related to the kidneys and urinary tract

  • How symptoms of kidney failure change as function declines

  • How uraemia affects the nervous system

  • How gout is linked to kidney disease

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. National Institute for Health and Care Excellence. Lower urinary tract symptoms in men: management. Clinical guideline [CG97]. https://www.nice.org.uk/Guidance/CG97.

  2. Public Health England. Prostate cancer risk management programme: overview. Last updated 29 March 2016. https://www.gov.uk/guidance/prostate-cancer-risk-management-programme-overview.

  3. National Health Service. Urinary incontinence. https://www.nhs.uk/conditions/urinary-incontinence/symptoms/.

  4. Weprin BE, Oakes WJ. Coccygeal pits. Pediatrics. 2000;105(5):E69. https://pediatrics.aappublications.org/content/105/5/e69.

    Article  CAS  Google Scholar 

  5. National Institute for Health and Care Excellence. Clinical knowledge summary. Bedwetting (enuresis). https://cks.nice.org.uk/bedwetting-enuresis.

  6. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3:1–150. http://kdigo.org/home/guidelines/ckd-evaluation-management.

    Article  Google Scholar 

  7. Artom M, Moss-Morris R, Caskey F, Chilcot J. Fatigue in advanced kidney disease. Kidney Int. 2014;86:497–505. https://doi.org/10.1038/ki.2014.86. https://www.kidney-international.org/article/S0085-2538(15)30331-8/fulltext.

    Article  CAS  PubMed  Google Scholar 

  8. Sukul N, Speyer E, Tu C, Bieber BA, Li Y, Lopes AA, Asahi K, Mariani L, Laville M, Rayner HC, Stengel B, Robinson BM, Pisoni RL, CKDopps and CKD-REIN Investigators. Pruritus and patient reported outcomes in non-dialysis CKD. Clin J Am Soc Nephrol. 2019;14(5):673–81. https://doi.org/10.2215/CJN.09600818. Epub 2019 Apr 11. https://cjasn.asnjournals.org/content/14/5/673.long.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Rayner HC, Larkina M, Wang M, Graham-Brown M, van der Veer SN, Ecder T, Hasegawa T, Kleophas W, Bieber BA, Tentori F, Robinson BM, Pisoni RL. International comparisons of prevalence, awareness, and treatment of pruritus in people on hemodialysis. Clin J Am Soc Nephrol. 2017;12(12):2000–7. https://doi.org/10.2215/CJN.03280317. https://cjasn.asnjournals.org/content/clinjasn/12/12/2000.full.pdf.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Pisoni RL, Wikstrom B, Elder SJ, et al. Pruritus in haemodialysis patients: international result from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant. 2006;21:3495–505. http://ndt.oxfordjournals.org/content/21/12/3495.full.

    Article  Google Scholar 

  11. Aresi G, Rayner HC, Hassan L, Burton JO, Mitra S, Sanders C, van der Veer S. Reasons for underreporting of uremic pruritus in people with chronic kidney disease: a qualitative study. J Pain Symptom Manage. 2019;58(4):578–586.e2. https://doi.org/10.1016/j.jpainsymman.2019.06.010. https://www.jpsmjournal.com/article/S0885-3924(19)30343-4/fulltext.

    Article  PubMed  Google Scholar 

  12. Papoiu AD, Emerson NM, Patel TS, Kraft RA, Valdes-Rodriguez R, Nattkemper LA, Coghill RC, Yosipovitch G. Voxel-based morphometry and arterial spin labeling fMRI reveal neuropathic and neuroplastic features of brain processing of itch in end-stage renal disease. J Neurophysiol. 2014;112(7):1729–38. https://doi.org/10.1152/jn.00827.2013. Epub 2014 Jun 18. https://www.physiology.org/doi/pdf/10.1152/jn.00827.2013.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Gunal AI, Ozalp G, Yoldas TK, Gunal SY, Kirciman E, Celiker H. Gabapentin therapy for pruritus in haemodialysis patients: a randomized, placebo-controlled, double-blind trial. Nephrol Dial Transplant. 2004;19:3137–9. http://ndt.oxfordjournals.org/content/19/12/3137.full.pdf.

    Article  CAS  Google Scholar 

  14. Yue J, Jiao S, Xiao Y, Ren W, Zhao T, Meng J. Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. Int Urol Nephrol. 2015;47(1):161–7. https://doi.org/10.1007/s11255-014-0795-x. http://download.springer.com/static/pdf/823/art%253A10.1007%252Fs11255-014-0795-x.pdf?auth66=1425491040_c2475cbe1d116e09fa6998febcb2b056&ext=.pdf.

    Article  CAS  PubMed  Google Scholar 

  15. Rayner H, Baharani J, Smith S, Suresh V, Dasgupta I. Uraemic pruritus: relief of itching by gabapentin and pregabalin. Nephron Clin Pract. 2013;122(3–4):75–9. https://doi.org/10.1159/000349943. https://www.karger.com/Article/FullText/349943.

    Article  CAS  Google Scholar 

  16. Vargas-Santos AB, Neogi T. Management of gout and hyperuricemia in CKD. Am J Kidney Dis. 2017;70(3):422–39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572666.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Rayner, H.C., Thomas, M.E., Milford, D.V. (2020). How Are You Feeling? Symptoms of Kidney Disease . In: Understanding Kidney Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-43027-6_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-43027-6_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-43026-9

  • Online ISBN: 978-3-030-43027-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics