Experimental Validations

  • Kerim Türe
  • Catherine Dehollain
  • Franco Maloberti
Part of the Analog Circuits and Signal Processing book series (ACSP)


In this chapter, system integration of the fabricated integrated circuits for remote powering and wireless data communication blocks of the implantable neural monitoring system is presented. The importance of biomedical packaging is discussed, and an easy-to-apply solution for the proposed system is introduced. The functionality of the remote powering system and the narrowband transmitter is verified in vivo with implantation into the rat. A receiver circuit for wireless data communication is designed with discrete components. Finally, the proposed system is validated with off-the-shelve components and in vivo measurements of neural recordings.


Animal experiment Biocompatibility Biomedical packaging Conformité Européenne (CE) Cortex Epoxy Food and drug administration (FDA) Integrated circuit International organization for standardization (ISO) In vivo characterization Multielectrode array (MEA) Off-the-shelve components Parylene-C Remote powering Wireless data communication 


  1. 1.
    Hassler C, Boretius T, Stieglitz T (2011) Polymers for neural implants. J Polym Sci Part B: Polym Phys 49:18–33CrossRefGoogle Scholar
  2. 2.
    E32-600-10-100 NeuroNexus. In: NeuroNexus. Accessed 11 Dec 2018

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Kerim Türe
    • 1
  • Catherine Dehollain
    • 1
  • Franco Maloberti
    • 2
  1. 1.École Polytechnique Fédérale de LausanneLausanneSwitzerland
  2. 2.University of PaviaPaviaItaly

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