Numerical Investigation of Gas-Liquid Two-Phase Flow in a Stirred Tank

  • Nao Ishida
  • Al Abri Mohammed
  • Atsushi Sekimoto
  • Yasunori OkanoEmail author
  • Shinya Abe
  • Kosuke Tanaka
Conference paper
Part of the Lecture Notes in Networks and Systems book series (LNNS, volume 101)


Gas-liquid stirred tanks are widely used in various chemical engineering processes such as fermentation and pharmaceutical production. In the mixing process for fermentation, aerobic microbes produce high polymer compounds from oxygen and carbon sources which need to be supplied by agitation and aeration in a tank. It is essential to supply a sufficient and uniform amount of nutrients to provide high quality and quantity products, and hence, it is necessary to optimize the shape and operating conditions of the stirring tank to mix gas and materials in the liquid sufficiently and uniformly. However, it is difficult to obtain a guideline for the design of plant-scale tanks from laboratory-scale experiments because experimental measurements cannot provide the detailed distribution of materials. The present study aims to obtain a guideline for an optimized design by developing computational fluid dynamics (CFD) simulation of the gas-liquid two-phase flow in the stirred tank and investigating the mass transfer inside the stirred tank in detail. Applying k-ω shear stress transport (SST) model, we calculate the gas-liquid flow in the stirred tank and estimate overall gas hold-up in comparison with experimental data.


Gas-liquid flow Stirred tank Gas hold-up Numerical simulation 



The computation was carried out using the computational resources of Research Institute for Information Technology, Kyushu University.


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Nao Ishida
    • 1
  • Al Abri Mohammed
    • 1
  • Atsushi Sekimoto
    • 1
  • Yasunori Okano
    • 1
    Email author
  • Shinya Abe
    • 2
  • Kosuke Tanaka
    • 2
  1. 1.Department of Materials Engineering ScienceOsaka UniversityToyonaka, OsakaJapan
  2. 2.KANEKATakasagoJapan

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