• Neusa Yuriko Sakai ValenteEmail author
  • Mai P. Hoang


In the hospitalized setting, hair loss, either telogen effluvium or anagen effluvium, is most commonly caused by drugs and anticancer therapy. Anticancer chemotherapy is a well-known cause of anagen effluvium. Other conditions associated with telogen effluvium include postpartum hormonal changes, medication, surgery, crash diet, hypothyroidism, and acute febrile illness. Pressure alopecia is a patchy, non-cicatricial, or cicatricial alopecia occurring on the scalp areas submitted to a prolonged pressure, either during surgery immobilization by coma. Diffuse hair loss can be the only manifestation of latent syphilis in the absence of other manifestations. Hair loss can present in various clinical patterns in patients with lupus erythematosus and half of those with systemic lupus erythematosus. These types of alopecia will be discussed in this chapter. Their histopathologic features are not specific; therefore, clinical pathologic correlation is essential.


Alopecia Tinea capitis Pressure alopecia Anagen effluvium Telogen effluvium Drug-induced alopecia Chemotherapy-induced alopecia Antitumor necrosis factor Tyrosine kinase inhibitor Tacrolimus Nilotinib Lupus erythematosus Syphilitic alopecia 


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Authors and Affiliations

  1. 1.Department of DermatologyHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, University of São PauloSão PauloBrazil
  2. 2.Department of PathologyMassachusetts General Hospital and Harvard Medical SchoolBostonUSA

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