Cutaneous Manifestations of HIV in Children
- 18 Downloads
Skin manifestations are common in HIV infected patients with a prevalence rate ranging from 36% to 52% in children and 41% to 94% in adults. At least 30% present with skin conditions as a manifestation of their underlying HIV and 90% manifest with skin conditions during the course of HIV. In addition, therapy with antiretroviral therapy is responsible for drug reactions and immune reconstitution syndrome which most commonly presents with skin lesions. Common dermatoses are more severe and recalcitrant to therapy in HIV infected patients; however, there may be skin conditions that are specific and occur only in the context of HIV infection. Thus, early recognition of skin lesions can prompt investigation and early management of HIV infection as well as recognition of failure and resistance to antiretroviral therapy.
KeywordsHIV and skin Infections Inflammatory Immune reconstitution Failure Drug reactions Early recognition
- 3.Paller A, Mancini A. Hurwitz’s pediatric dermatology. 4th ed. London: Elsevier; 2011. p. 632.Google Scholar
- 12.Siberry GK, Abzug MJ, Nachman S, Brady MT, Dominguez KL, Handelsman E, et al. Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: recommendations from the National Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics. Pediatr Infect Dis J. 2013;32(Suppl 2):i–KK4.CrossRefGoogle Scholar