Antimicrobial Endodontic Materials

  • Xiaogang Cheng
  • Xiaohua LiuEmail author


Bacteria and their by-products are the primary cause of pulpal and periapical diseases that are one of the most common oral diseases. Root canal treatment (RCT) is the most effective procedure to treat pulpal and periapical diseases with severe infection. RCT aims to eliminate the infection from root canals and place filling materials to seal the space to prevent reinfection. Because of the complicated anatomical structure of the tooth root canal, complete elimination of the bacteria that reside in a root canal and the dentinal tubules via mechanical preparation is extremely difficult, if not impossible. Therefore, antimicrobial endodontic materials are indispensable for infection elimination during RCT. Based on the procedure of RCT, different antimicrobial endodontic materials have been developed for root canal irrigation, medication, and obturation (sealing). This chapter discusses the antimicrobial endodontic biomaterials that are used during the three steps of the RCT. Advantages and limitations of each material are emphasized. In addition, recent developments and future research directions of antimicrobial endodontic biomaterials are presented.


Antimicrobial Endodontic Dental materials Root canal treatment Pulpal and periapical diseases Tooth 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Biomedical Sciences DepartmentTexas A&M University College of DentistryDallasUSA
  2. 2.Department of Operative Dentistry and EndodonticsSchool of Stomatology, The Fourth Military Medical UniversityXi’anPR China

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