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Automatic Newton Modeling in Clinical Pharmacology (15 Alfentanil Dosages, 15 Quinidine Time-Concentration Relationships)

  • Ton J. Cleophas
  • Aeilko H. Zwinderman
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  • 86 Downloads

Abstract

Traditional regression analysis selects a mathematical function, and, then, uses the data to find the best fit parameters. For example, the parameters a and b for a linear regression function with the equation y = a + bx have to be calculated according to

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Ton J. Cleophas
    • 1
  • Aeilko H. Zwinderman
    • 2
  1. 1.Department Medicine Albert Schweitzer HospitalDordrechtThe Netherlands
  2. 2.Academic Medical CenterDepartment Biostatistics and EpidemiologyAmsterdamThe Netherlands

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