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Fuzzy Logic for Improved Precision of Dose-Response Data (8 Induction Dosages)

  • Ton J. Cleophas
  • Aeilko H. Zwinderman
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Abstract

Fuzzy logic can handle questions to which the answers may be “yes” at one time and “no” at the other, or may be partially true and untrue. Pharmacodynamic data deal with questions like “does a patient respond to a particular drug dose or not”, or “does a drug cause the same effects at the same time in the same subject or not”. Such questions are typically of a fuzzy nature, and might, therefore, benefit from an analysis based on fuzzy logic.

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Ton J. Cleophas
    • 1
  • Aeilko H. Zwinderman
    • 2
  1. 1.Department Medicine Albert Schweitzer HospitalDordrechtThe Netherlands
  2. 2.Academic Medical CenterDepartment Biostatistics and EpidemiologyAmsterdamThe Netherlands

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