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Extracellular Vesicles

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Essential Current Concepts in Stem Cell Biology

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Abstract

Extracellular vesicles (EVs) are submicron-sized biological vesicles which can transfer complex information or signals from releasing cells to other cells or tissues in a targeted manner. EVs are released by basically all cell types and are detected in all body fluids. Due to their potential therapeutic and diagnostic potential, the EV research field has gained lots of attention and is growing rapidly especially within the last decade. In this chapter, we will summarize the history behind their discovery and the current knowledge about EV-related functions. Furthermore, we will elaborate on their therapeutic potential with a focus on regenerative medicine.

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Authors and Affiliations

  1. Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

    André Görgens & Bernd Giebel

  2. Clinical Research Center, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden

    André Görgens

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  1. André Görgens
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  2. Bernd Giebel
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Correspondence to André Görgens .

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Editors and Affiliations

  1. Department of Anatomy & Molecular Embryology, Ruhr-University Bochum, Bochum, Nordrhein-Westfalen, Germany

    Beate Brand-Saberi

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Görgens, A., Giebel, B. (2020). Extracellular Vesicles. In: Brand-Saberi, B. (eds) Essential Current Concepts in Stem Cell Biology. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-33923-4_13

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