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Challenges in PHAs Production at Mass Scale

  • Geeta GahlawatEmail author
Chapter
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

Polyhydroxyalkanoates (PHAs) biopolymers provide a suitable alternative to the synthetic plastics because of their biodegradability, biocompatibility and environment friendly manufacturing processes. PHAs are promising candidate for bio-based plastics because their material properties are quite similar to petroleum-based plastics and can be produced from renewable resources. However, the high production cost limit their application at industrial level. This book chapter discusses about the challenges faced by the society for the commercialization of biodegradable PHAs.

Keywords

Biodegradable polymers High cost Low concentration Recovery Economical production 

References

  1. Alves MI et al (2017) Poly (3-hydroxybutyrate)-P (3HB): review of production process technology. Ind Biotechnol 13(4):192–208CrossRefGoogle Scholar
  2. Braunegg G, Bona R, Koller M (2004) Sustainable polymer production. Polym Plast Technol Eng 43(6):1779–1793CrossRefGoogle Scholar
  3. Castilho LR, Mitchell DA, Freire DMG (2009) Production of polyhydroxyalkanoates (PHAs) from waste material and solid-state fermentation. Bioresour Technol 100:5996–6009CrossRefGoogle Scholar
  4. Cavalheiro JMBT et al (2012) Effect of cultivation parameters on the production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(3-hydroxybutyrate-4-hydroxybutyrate-3-hydroxyvalerate) by Cupriavidus necator using waste glycerol. Bioresour Technol 111:391–397CrossRefGoogle Scholar
  5. Chanprateep S (2010) Current trends in biodegradable polyhydroxyalkanoates. J Biosci Bioeng 110(6):621–632CrossRefGoogle Scholar
  6. Domski GJ, Rose JM, Coates GW, Bolig AD, Brookhart M (2007) Living alkene polymerization: new methods for the precision synthesis of polyolefins. Prog Polym Sci 32:30–92CrossRefGoogle Scholar
  7. Fiorese ML, Freitas F, Pais J, Ramos AM, de Aragão GM, Reis MA (2009) Recovery of polyhydroxybutyrate (PHB) from Cupriavidus necator biomass by solvent extraction with 1,2-propylene carbonate. Eng Life Sci 9(6):454–461CrossRefGoogle Scholar
  8. Gomez JG, Méndez BS, Nikel PI, Pettinari MJ, Prieto MA, Silva LF (2012) Making green polymers even greener: towards sustainable production of polyhydroxyalkanoates from agroindustrial by-products. (ed by Marian Petre) Adv Appl Biotechnol 41–62Google Scholar
  9. Ienczak JL, Schmidell W, de Aragão GMF (2013) High-cell-density culture strategies for polyhydroxyalkanoate production: a review. J Ind Microbiol Biotechnol 40(3–4):275–286CrossRefGoogle Scholar
  10. Jacquel N, Lo C-W, Wei Y-H, Wu H-S, Wang SS (2008) Isolation and purification of bacterial poly(3-hydroxyalkanoates). Biochem Eng J 39(1):15–27CrossRefGoogle Scholar
  11. Kim M, Cho KS, Ryu HW, Lee EG, Chang YK (2003) Recovery of poly (3-hydroxybutyrate) from high cell density culture of Ralstonia eutropha by direct addition of sodium dodecyl sulfate. Biotechnol Lett 25:55–59CrossRefGoogle Scholar
  12. Koller M et al (2008) Polyhydroxyalkanoate production from whey by Pseudomonas hydrogenovora. Bioresour Technol 99:4854–4863CrossRefGoogle Scholar
  13. López-Abelairas M, García-Torreiro M, Lú-Chau T, Lema JM, Steinbüchel A (2015) Comparison of several methods for the separation of poly (3-hydroxybutyrate) from Cupriavidus necator H16 cultures. Biochem EngJ 93:250–259CrossRefGoogle Scholar
  14. Nath A, Dixit M, Bandiya A, Chavda S, Desai AJ (2008) Enhanced PHB production and scale up studies using cheese whey in fed batch culture of Methylobacterium sp. ZP24. Bioresour Technol 99(13):5749–5755CrossRefGoogle Scholar
  15. Pan W, Perrotta JA, Stipanovic AJ, Nomura CT, Nakas JP (2012) Production of polyhydroxyalkanoates by Burkholderia cepacia ATCC 17759 using a detoxified sugar maple hemicellulosic hydrolysate. J Ind Microbiol Biotechnol 39:459–469CrossRefGoogle Scholar
  16. Penloglou G, Chatzidoukas C, Kiparissides C (2012) Microbial production of polyhydroxybutyrate with tailor-made properties: an integrated modelling approach and experimental validation. Biotechnol Adv 30(1):329–337CrossRefGoogle Scholar
  17. Wang Y, Chen G-Q (2017) Polyhydroxyalkanoates: sustainability, production and industrialization. In: Tang C, Ryu CY (eds) Sustainable polymers from biomass. Wiley VCH, Weinheim, Germany, p 14CrossRefGoogle Scholar
  18. Wang Y, Yin J, Chen G-Q (2014) Polyhydroxyalkanoates, challenges and opportunities. Curr Opin Biotechnol 30:59–65CrossRefGoogle Scholar

Copyright information

© The Author(s), under exclusive license to Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of MicrobiologyPanjab UniversityChandigarhIndia

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