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The Influence of Semiconductor Nanoparticles Upon the Activity of Mesenchymal Stem Cells

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4th International Conference on Nanotechnologies and Biomedical Engineering (ICNBME 2019)

Part of the book series: IFMBE Proceedings ((IFMBE,volume 77))

Abstract

In this paper, we report on the viability and proliferation of mesenchymal stem cells after exposure to different types of semiconductor nanoparticles. The nanoparticles used for the tests are based on GaN thin layers grown on commercial ZnO and ZnFe2O4 nanoparticles. Different quantities of nanoparticles incubated with mesenchymal stem cells influence the metabolic activity of cells, which was assessed by the MTT assay. The cytotoxic effect of ZnO nanoparticles on MSC was demonstrated and no harmful effect of the other materials.

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Acknowledgements

The authors acknowledge the support from the Ministry of Education, Culture and Research of the Republic of Moldova under the Grants #18TC, #15.817.02.29A and #15.817.04.04F. This work has received partial funding from the European Union’s Horizon 2020 research and innovation programme under grant #810652 (NanoMedTwin project).

Conflict of Interest The authors declare that they have no conflict of interest.

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Braniste, T. et al. (2020). The Influence of Semiconductor Nanoparticles Upon the Activity of Mesenchymal Stem Cells. In: Tiginyanu, I., Sontea, V., Railean, S. (eds) 4th International Conference on Nanotechnologies and Biomedical Engineering. ICNBME 2019. IFMBE Proceedings, vol 77. Springer, Cham. https://doi.org/10.1007/978-3-030-31866-6_108

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  • DOI: https://doi.org/10.1007/978-3-030-31866-6_108

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-31865-9

  • Online ISBN: 978-3-030-31866-6

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