Solution-Based Dosage Forms and Sterile Products
This chapter expands upon the concept of drug solubility and dissolution as it relates to dosage form design. Excipients utilized in solution-based dosage forms and parenteral products are discussed in detail, including solvents, cosolvents, antioxidants, preservatives, complexing agents, and surfactants. Special considerations which must be made for parenteral dosage forms are introduced. Lastly, a review of lyophilization and sterilization techniques is provided.