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Epidemiology of Sinonasal Cancer

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Pathology of Sinonasal Tumors and Tumor-Like Lesions

Abstract

Sinonasal cancers (SNCs) represent less than the 0.2% of all cancers yearly diagnosed in the world and about 3.6% of all malignancies arising in the head and neck area. Despite this low frequency, a great variety of histological types may be found. Sinonasal cancers are cancers with an aggressive clinical behaviour which frequently pose a number of problems regarding the interpretation of diagnostic findings and the treatment. SNCs may be classified as rare cancer, but the low absolute risk in the general population effectively contrasts with the high relative risks for specific chemical exposures and occupational settings. Wood and leather dust exposure, nickel compounds, and tobacco smoking are associated with increasing risk of SNC, and International Cancer Research Agency (IARC) classified these agents as carcinogenic to humans (Group 1). Other occupational exposures are also suggested to be associated with sinonasal cancer (formaldehyde, chromium (VI) compounds, textile industry, farming and construction). Epidemiological surveillance of SNC cases and their occupational history is fundamental for monitoring the occurrence of the disease in exposed workers in industrial sectors. Implementation of risk reduction strategies and the prevention of diseases caused by workplace exposures are important public health objectives. In this chapter, epidemiology of sinonasal cancer is presented.

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Author information

Authors and Affiliations

  1. Unit of Environmental and Occupational Epidemiology, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy

    Lucia Miligi & Sara. Piro

  2. Tuscany Cancer Registry, Clinical and Descriptive Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy

    Carlotta Buzzoni

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  1. Lucia Miligi
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  2. Carlotta Buzzoni
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  3. Sara. Piro
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Correspondence to Lucia Miligi .

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Editors and Affiliations

  1. Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

    Alessandro Franchi

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Miligi, L., Buzzoni, C., Piro, S. (2020). Epidemiology of Sinonasal Cancer. In: Franchi, A. (eds) Pathology of Sinonasal Tumors and Tumor-Like Lesions. Springer, Cham. https://doi.org/10.1007/978-3-030-29848-7_1

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  • DOI: https://doi.org/10.1007/978-3-030-29848-7_1

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