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Biosynthesized Metallic Nanoparticles as Emerging Cancer Theranostics Agents

  • Muhammad OvaisEmail author
  • Ali Talha Khalil
  • Muhammad Ayaz
  • Irshad Ahmad
Chapter

Abstract

Cancer is considered as a great health challenge liable for outstripped demises worldwide. Currently it is treated mainly by chemotherapy and radiotherapy. However, there is a perpetual demand for the development of novel therapeutic drugs to combat this devastating disease. In this regard nanomedicine can provide an alternative platform for its diagnosis and treatment but its conventional synthesis through physiochemical methods has several shortcomings like high cost, energy intensive, and toxicity concerns. Consequently, the green synthesis of biogenic metallic nanoparticles (MNPs) from plants provides an alternate paradigm which has been proved safer, eco-friendly, energy proficient, inexpensive, and less toxic in nature. Additionally, the green MNPs have multipurpose biomedical applications like drug delivery agents, anticancerous mediators, photothermal therapy, and bio-imaging. This chapter will provide ample information on the current status of green MNPs, its anticancerous mechanisms, and efficiency in cancer diagnosis. Other issues like polydispersity and toxicity are also highlighted. Keeping in view all of the challenges, the authors anticipate biogenic MNPs may contribute to shift the paradigm toward development of novel nanomedicine that can prove as biocompatible theranostic agents in near future.

Keywords

Metal nanoparticles Bionanomaterials Cancer theranostics Green synthesis Biocompatibility 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Muhammad Ovais
    • 1
    • 2
    Email author
  • Ali Talha Khalil
    • 3
  • Muhammad Ayaz
    • 4
  • Irshad Ahmad
    • 5
  1. 1.CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST)BeijingPeople’s Republic of China
  2. 2.University of Chinese Academy of SciencesBeijingPeople’s Republic of China
  3. 3.Department of Eastern Medicine and SurgeryQarshi UniversityLahorePakistan
  4. 4.Department of PharmacyUniversity of MalakandChakdaraPakistan
  5. 5.Department of Life SciencesKing Fahd University of Petroleum and Minerals (KFUPM)DhahranSaudi Arabia

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