Advertisement

Hysteroscopy and Infertility

  • Attilio Di Spiezio Sardo
  • Alessandro Conforti
  • Enrica Mastantuoni
  • Carlo Alviggi
  • Jose Jimenez
Chapter
  • 53 Downloads

Abstract

The clinical relevance of hysteroscopy in the diagnosis and treatment of uterine factors and its role in the infertility workup is still the topic of discussion in the scientific community.

Thanks to its potential capability to “see and treat” many of the uterine pathologies and to improve reproductive outcomes and reduce time to pregnancy, its importance has been reconsidered in the evaluation of infertile couples.

The objective of this chapter is to highlight the efficacy of diagnostic and/or operative hysteroscopy in improving the pregnancy outcome of infertile women, through diagnosis and treatment of some uterine anomalies.

Keywords

Hysteroscopy Infertility Pregnancy rate Live birth rate Adenomyosis Endometritis Isthmocele Uterine malformation 

References

  1. 1.
    Revel A. Defective endometrial receptivity. Fertil Steril. 2012;97:1028–32.CrossRefGoogle Scholar
  2. 2.
    Donaghay M, Lessey BA. Uterine receptivity: alterations associated with benign gynecological disease. Semin Reprod Med. 2007;25:461–75.CrossRefGoogle Scholar
  3. 3.
    Di Spiezio Sardo A, Di Carlo C, Minozzi S, Spinelli M, Pistotti V, Alviggi C, et al. Efficacy of hysteroscopy in improving reproductive outcomes of infertile couples: a systematic review and meta-analysis. Hum Reprod Update. 2016;22:479–96.CrossRefGoogle Scholar
  4. 4.
    Salazar CA, Isaacson K. Office operative hysteroscopy: an update. J Minim Invasive Gynecol. 2018;25:199–208.CrossRefGoogle Scholar
  5. 5.
    National Collaborating Centre for Women’s and Children’s Health. National Institute for Health and Clinical Excellence: Guidance. Fertility: Assessment and Treatment for People with Fertility Problems. London: Royal College of Obstetricians & Gynaecologists National Collaborating Centre for Women’s and Children’s Health; 2013.Google Scholar
  6. 6.
    ASRM. Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril. 2015;103:e44–50.CrossRefGoogle Scholar
  7. 7.
    Mairos J, Di Martino P. Office Hysteroscopy. An operative gold standard technique and an important contribution to Patient Safety. Gynecol Surg. 2016;13:111–4.CrossRefGoogle Scholar
  8. 8.
    Alviggi C, Humaidan P, Howles CM, Tredway D, Hillier SG. Biological versus chronological ovarian age: Implications for assisted reproductive technology. Reprod Biol Endocrinol. 2009;7:101.CrossRefGoogle Scholar
  9. 9.
    Takahashi K, Mukaida T, Tomiyama T, Oka C. High pregnancy rate after hysteroscopy with irrigation in uterine cavity prior to blastocyst transfer in patients who have failed to conceive after blastocyst transfer. Fertil Steril. 2000;74:S206.CrossRefGoogle Scholar
  10. 10.
    Almog B, Shalom-Paz E, Dufort D, Tulandi T. Promoting implantation by local injury to the endometrium. Fertil Steril. 2010;94:2026–9.CrossRefGoogle Scholar
  11. 11.
    Mirkin S, Arslan M, Churikov D, Corica A, Diaz JI, Williams S, et al. In search of candidate genes critically expressed in the human endometrium during the window of implantation. Hum Reprod. 2005;20:2104–17.CrossRefGoogle Scholar
  12. 12.
    Coughlan C, Ledger W, Wang Q, Liu F, Demirol A, Gurgan T, et al. Recurrent implantation failure: definition and management. Reprod Biomed Online. 2014;28:14–38.CrossRefGoogle Scholar
  13. 13.
    Kitaya K, Matsubayashi H, Yamaguchi K, Nishiyama R, Takaya Y, Ishikawa T, et al. Chronic endometritis: potential cause of infertility and obstetric and neonatal complications. Am J Reprod Immunol (New York, NY: 1989). 2016;75:13–22.CrossRefGoogle Scholar
  14. 14.
    Michels TC. Chronic endometritis. Am Fam Physician. 1995;52:217–22.PubMedGoogle Scholar
  15. 15.
    Paavonen J, Aine R, Teisala K, Heinonen PK, Punnonen R, Lehtinen M, et al. Chlamydial endometritis. J Clin Pathol. 1985;38:726–32.CrossRefGoogle Scholar
  16. 16.
    Edmondson N, Bocking A, Machin G, Rizek R, Watson C, Keating S. The prevalence of chronic deciduitis in cases of preterm labor without clinical chorioamnionitis. Pediatr Dev Pathol. 2009;12:16–21.CrossRefGoogle Scholar
  17. 17.
    Cicinelli E, Matteo M, Trojano G, Mitola PC, Tinelli R, Vitagliano A. Chronic endometritis in patients with unexplained infertility: prevalence and effects of antibiotic treatment on spontaneous conception. Am J Reprod Immunol. 2018;79  https://doi.org/10.1111/aji.12782.CrossRefGoogle Scholar
  18. 18.
    Di Spiezio Sardo A, Calagna G, Santangelo F, Zizolfi B, Tanos V. The role of hysteroscopy in the diagnosis and treatment of adenomyosis. Biomed Res Int. 2017;2017:2518396.CrossRefGoogle Scholar
  19. 19.
    Levgur M, Abadi MA, Tucker A. Adenomyosis: symptoms, histology, and pregnancy terminations. Obstet Gynecol. 2000;95:688–91.Google Scholar
  20. 20.
    Basak S, Saha A. Adenomyosis: still largely under-diagnosed. J Obstet Gynaecol. 2009;29:533–5.CrossRefGoogle Scholar
  21. 21.
    Vercellini P, Consonni D, Dridi D, Bracco B, Frattaruolo MP, Somigliana E. Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis. Hum Reprod. 2014;29:964–77.CrossRefGoogle Scholar
  22. 22.
    Vannuccini S, Tosti C, Carmona F, Huang SJ, Chapron C, Guo S-W, et al. Pathogenesis of adenomyosis: an update on molecular mechanisms. Reprod Biomed Online. 2017;35:592–601.CrossRefGoogle Scholar
  23. 23.
    Vercellini P, Consonni D, Dridi D, Bracco B, Frattaruolo MP, Somigliana E. Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis. Hum Reprod. 2014;96(6):715–26.Google Scholar
  24. 24.
    Saravelos SH, Cocksedge KA, Li TC. Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal. Hum Reprod Update. 2008;14:415–29.CrossRefGoogle Scholar
  25. 25.
    Grimbizis GF, Di Spiezio Sardo A, Saravelos SH, Gordts S, Exacoustos C, Van Schoubroeck D, et al. The Thessaloniki ESHRE/ESGE consensus on diagnosis of female genital anomalies. Gynecol Surg. 2016;13:1–16.CrossRefGoogle Scholar
  26. 26.
    Di Spiezio Sardo A, Florio P, Nazzaro G, Spinelli M, Paladini D, Di Carlo C, et al. Hysteroscopic outpatient metroplasty to expand dysmorphic uteri (HOME-DU technique): a pilot study. Reprod Biomed Online. 2015;30:166–74.CrossRefGoogle Scholar
  27. 27.
    Fernandez H, Garbin O, Castaigne V, Gervaise A, Levaillant JM. Surgical approach to and reproductive outcome after surgical correction of a T-shaped uterus. Hum Reprod. 2011;26:1730–4.CrossRefGoogle Scholar
  28. 28.
    Di Spiezio Sardo A, Zizolfi B, Calagna G, Giampaolino P, Paolella F, Bifulco G. Hysteroscopic isthmoplasty: step-by-step technique. J Minim Invasive Gynecol. 2018;25:338–9.CrossRefGoogle Scholar
  29. 29.
    Tower AM, Frishman GN. Cesarean scar defects: an underrecognized cause of abnormal uterine bleeding and other gynecologic complications. J Minim Invasive Gynecol. 2013;20:562–72.CrossRefGoogle Scholar
  30. 30.
    Xie H, Wu Y, Yu F, He M, Cao M, Yao S. A comparison of vaginal surgery and operative hysteroscopy for the treatment of cesarean-induced isthmocele: a retrospective review. Gynecol Obstet Invest. 2014;77:78–83.CrossRefGoogle Scholar
  31. 31.
    Florio P, Filippeschi M, Moncini I, Marra E, Franchini M, Gubbini G. Hysteroscopic treatment of the cesarean-induced isthmocele in restoring infertility. Curr Opin Obstet Gynecol. 2012;24:180–6.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Attilio Di Spiezio Sardo
    • 1
  • Alessandro Conforti
    • 2
  • Enrica Mastantuoni
    • 2
  • Carlo Alviggi
    • 2
  • Jose Jimenez
    • 3
  1. 1.Division of Obstetrics and Gynecology, Department of Public HealthSchool of Medicine, University of Naples “Federico II”NaplesItaly
  2. 2.Department of Neuroscience, Reproductive Science and OdontostomatologyUniversity of Naples Federico IINaplesItaly
  3. 3.Unifertes Fertility UnitCaracasVenezuela

Personalised recommendations