Antimicrobial Activity of Nanomaterials

  • Bablu Lal Rajak
  • Rahul Kumar
  • Manashjit Gogoi
  • Sanjukta Patra
Part of the Environmental Chemistry for a Sustainable World book series (ECSW, volume 39)


The World Health Organization reports that millions of deaths occurring worldwide are because of infectious diseases caused by bacteria, viruses, fungi and parasites. The existing therapeutics is not adequate enough to fight against these diseases and their prolonged uses have led to the development of drug-resistant strains which are even more difficult to control. Hence, the need for an alternative approach is growing. Development of nanotechnology, especially nanostructured particles and formulations, is providing new opportunities to combat these infectious diseases more effectively. Nanomaterials have unique physicochemical properties like tuneable size, large surface to volume ratio, high reactivity, biocompatibility and functionalizable surface area. These properties are applied to facilitate the applications of antimicrobial drugs, thereby overcoming some of the limitations of traditional antimicrobial therapeutics. Moreover, the therapeutic effect and drug delivery approach of these nanomaterials have emerged as an innovative and promising alternative that enhance therapeutic effectiveness against pathogenic microorganisms and minimize undesirable side effects of the drugs. In order to enumerate the antimicrobial effect of these nanomaterials, this chapter is designed to discuss commonly used nanomaterials such as lipid vesicle dendrimers, polymeric and inorganic nanoparticles, carbon nanostructures, quantum dots, electrospun nanofibres, nanoclays, etc. against infectious diseases.


Antimicrobial Dendrimers Lipid vesicles Nanoclays Nanofibers Quantum dots 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Biomedical EngineeringNorth Eastern Hill UniversityShillongIndia
  2. 2.Department of NanotechnologyNorth Eastern Hill UniversityShillongIndia
  3. 3.Department of Biosciences and BioengineeringIndian Institute of Technology GuwahatiNorth GuwahatiIndia

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