Space Exploration and Travel, Future Technologies for Inflight Monitoring and Diagnostics

  • Jean-Pol FrippiatEmail author


Astronauts have been found to suffer from weakened immune systems. This phenomenon is frequently associated to latent virus reactivation. Maintaining crew health is therefore a concern to enable future long-term space missions such as those to Mars and beyond. Indeed, a Mars mission will imply 6 months of travel each way plus the surface stay. Thus, future space exploration needs innovative technologies to monitor health and perform personalized diagnostic and medicine. This chapter reviews some of the effects of spaceflight on the immune system and microorganisms, describes Earth-based models used to study the effects of such harsh environment, presents constraints associated to inflight analyses, biosensors for astronauts’ health inflight monitoring and some high-throughput “omics” technologies that are sufficiently developed to be ready for deployment and use soon onboard a spacecraft.


Immunosuppression Virus Omics Personalized medicine Diagnostic Biosensor Miniaturization Automatic devices Extreme conditions Spaceflight 



JPF and his team acknowledge support from the French Space Agency (CNES), the European Space Agency (ESA), the French Ministry of Higher Education and Research, the Université de Lorraine, the Région Lorraine and the “Impact Biomolecules” project of the “Lorraine Université d’Excellence” (Investissements d’avenir – ANR).


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Stress Immunity Pathogens Laboratory, EA 7300, Faculty of Medicine, Université de LorraineVandœuvre-lès-NancyFrance

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