Oestrogen Replacement Therapy
After menopause, oestrogen levels within a women’s body decrease. The vagina is normally colonised with Lactobacillus, a type of “good bacteria”, and their levels are maintained by oestrogen. Lactobacillus creates lactic acid, thus producing an acidic microenvironment within the vagina, protecting against harmful uropathogens from colonising. The loss of this oestrogen stimulation decreases the levels of lactobacillus within the vaginal wall epithelium, and thus the usual low pH acidic environment is lost, increasing the risk of UTIs in post-menopausal women.