From Heartburn to Lung Fibrosis and Beyond

  • Benjamin E. HaithcockEmail author


The relationship between gastroesophageal reflux disease (GERD) and end-stage lung disease (ESLD) is complex. This relationship remains a challenge to both the clinician and the patients. It is also a target for significant research. The purpose of this chapter is to describe the role of GERD in lung pathology that results in ESLD. This chapter will also review the pathophysiology resulting in chronic lung allograft dysfunction (CLAD) and its relationship to post-lung transplant GERD and the role of early anti-reflux surgery in patients with ESLD and after lung transplant.


Gastroesophageal reflux disease End-stage lung disease Idiopathic pulmonary fibrosis Chronic lung allograft dysfunction Lung transplant 


Conflict of Interest

The author has no conflict of interest to declare.


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of North CarolinaChapel HillUSA

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