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LABS Project

  • Bruce M. WolfeEmail author
  • Elizaveta Walker
Chapter

Abstract

In response to the growing rate of severe obesity and its consequences, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) funded the development of the Longitudinal Assessment of Bariatric Surgery (LABS) consortium to address some of the many questions related to the safety and efficacy of bariatric surgery. Comprised of six clinical centers and one data coordinating center with a governing body, LABS was a multicenter, observational cohort study with strategically designed protocols for data collection and maintenance. Three phases of the LABS study (LABS-1, LABS-2, and LABS-3) assessed the short- and longer-term risks and benefits of bariatric surgery and its associated outcomes and also examined several underlying mechanisms of effect in more detail. Ancillary studies include Teen-LABS and other approved protocols utilizing this extensive 7-year biospecimen and dataset.

Keywords

Obesity Bariatric surgery Longitudinal study Observational cohort Obesity-associated comorbidities Long-term weight loss Physical activity Roux-en-Y gastric bypass Laparoscopic adjustable gastric banding Diabetes remission Eating behaviors 

Notes

Acknowledgments

This chapter is based upon information originally provided in the published results of the LABS consortium study: Belle [13], Belle et al. [12], Belle et al. [38], Flum et al. [42], Smith et al. [43], Inabnet et al. [46], Smith et al. [47], Gosman et al. [53], King et al. [60], King et al. [65], Wolfe et al. [66], Kleiner [62], Belle et al. [48], Mackey et al. [49], Khan et al. [52], and Gourash et al. [71].

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Authors and Affiliations

  1. 1.Department of SurgeryOregon Health & Science UniversityPortlandUSA

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