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Management of Strongyloides Hyperinfection Syndrome

  • Shijing JiaEmail author
  • Hedwig S. Murphy
  • Melissa A. Miller
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  • 3 Downloads

Abstract

Strongyloides stercoralis is an infectious helminth endemic to the tropics and subtropics, and can be seen in immigrants and returning travelers. Symptoms of acute infection involve organs of the typical life cycle of the nematode. In milder forms of chronic infections, strongyloides is capable of persisting in a host for years to decades. Severe strongyloidiasis includes the hyperinfection syndrome and disseminated infection, and occurs most frequently in the immunocompromised and immunosuppressed populations. We illustrate a case of severe strongyloidiasis, discuss clinical manifestations and diagnosis of infection, and present the evidence for treatment options. The key to successful therapy is early recognition of disease, and prompt diagnosis in high risk patients.

Keywords

Strongyloides Strongyloides stercoralis Severe strongyloidiasis Strongyloides hyperinfection Disseminated strongyloides infection Strongyloides treatment Ileus Helminthic infections 

Notes

Acknowledgments

Disclosure: The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of the Agency for Healthcare Research and Quality (AHRQ). No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Shijing Jia
    • 1
    Email author
  • Hedwig S. Murphy
    • 2
  • Melissa A. Miller
    • 3
  1. 1.Internal Medicine, Pulmonary and Critical CareUniversity of MichiganAnn ArborUSA
  2. 2.Department of PathologyUniversity of Michigan and Veterans Affairs Ann Arbor Health SystemAnn ArborUSA
  3. 3.Division of Healthcare-Associated InfectionsCenter for Quality Improvement and Patient Safety, Agency for Healthcare Research and QualityRockvilleUSA

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