• Glenda Euceda
  • Benjamin Keveson
  • Garth W. GarrisonEmail author


Urosepsis, often termed sepsis of a urinary source, is a commonly encountered diagnosis in the ICU accounting for approximately 30% of cases of sepsis worldwide. It can present with or without urinary tract obstruction. The diagnosis is typically made by demonstrating signs and symptoms of urinary tract infection in a patient with sepsis or septic shock. Management specific to urosepsis includes therapies common to treatment of sepsis in general: early recognition, resuscitation, and early appropriate antibiotic administration. In urosepsis, recognition and amelioration of urinary obstruction plays an important role in management. Urinary obstruction can be identified by CT or ultrasound. Relieving urinary obstruction can be accomplished percutaneously, surgically, or via cystoscopy. Conflicting data exists for the appropriate up-front antibiotic regimen, indications for imaging, and the most appropriate method for intervention when obstruction is present. In this chapter, the diagnosis and management of urosepsis will be discussed. The conflicting data on antibiotics, imaging, and intervention will be addressed.


Sepsis Urinary tract infection Pyuria Urosepsis Urinary obstruction Nephrostomy Cystoscopy Urinary catheter Ureteral stent 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Glenda Euceda
    • 1
  • Benjamin Keveson
    • 2
  • Garth W. Garrison
    • 1
    Email author
  1. 1.University of Vermont Medical CenterBurlingtonUSA
  2. 2.Carolinas HealthCare-PinevillePinevilleUSA

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