Acute and Acute-on-Chronic Respiratory Failure: Impact of Chronic Lung Comorbidities

  • Filippo Luca Fimognari


Acute respiratory deteriorations are frequent and dangerous events in patients with lung comorbidities. The identification of the underlying cause(s) is challenging, also owing to chronic and unrecognized imaging and functional lung abnormalities. Oxygen therapy is the first support, but is burdened with possible complications and risk of failure. Non-invasive ventilation and high-flow nasal cannula oxygen therapy are important therapeutic resources.



Acute-on-chronic acute respiratory failure


Acute respiratory distress syndrome


Acute respiratory failure


Carbon dioxide


Chronic obstructive pulmonary disease


Conventional oxygen therapy


Computed tomography


Forced expiratory volume in the first second


Fraction of inspired oxygen


Forced vital capacity


High-flow nasal cannula


Idiopathic pulmonary fibrosis


Non-invasive ventilation


Restrictive lung disease




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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Filippo Luca Fimognari
    • 1
  1. 1.Division of Acute GeriatricsAnnunziata-Mariano Santo-S. Barbara HospitalCosenzaItaly

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