Pruritic Blisters

  • Anupam Das
  • Piyush Kumar


  • Chronic bullous disease of childhood (CBDC) and linear IgA disease are similar to one another in histology

  • CBDC begins in childhood and is also called the childhood linear IgA disease

  • Cutaneous lesions in CBDC usually heal without scarring

  • CBCD may show spontaneous remission and mean duration of disease in childhood is about 3.9 years

  • Mild cases and oral lesions respond well to topical corticosteroids while severe cases respond to dapsone or sulfapyridine


Chronic bullous disease of childhood Linear IgA disease Corticosteroids Dapsone Sulfapyridine 


  1. 1.
    Zone JJ, Taylor TB, Meyer LJ, Petersen MJ. The 97 kDa linear IgA bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2. J Invest Dermatol. 1998;110(3):207–10.CrossRefGoogle Scholar
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    Norris IN, Haeberle MT, Callen JP, Malone JC. Generalized linear IgA dermatosis with palmar involvement. Dermatol Online J. 2015;21:9.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Anupam Das
    • 1
  • Piyush Kumar
    • 2
  1. 1.Department of DermatologyKPC Medical CollegeKolkataIndia
  2. 2.Department of DermatologyKatihar Medical CollegeKatiharIndia

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