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Liver Transplantation Who Developed Pancytopenia Post-transplantation

  • Soumya Pandey
  • Terry HarvilleEmail author
Chapter

Abstract

  • Once the donor becomes deceased, the countdown sets off for the organ to be carefully harvested, packaged, delivered to a transport facility, and finally surgically placed

  • The cold-ischemic time allowed for a donor liver is up to 12 h

  • The liver is a large repository of donor lymphocytes and as many as 2% of patients receiving donor livers might develop graft versus host disease

Keywords

Graft versus host disease Cold-ischemic time Orthotopic liver transplantation 

References

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    Brent L. A history of transplantation immunology. San Diego: Academic Press Inc.; 1996.Google Scholar
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    Cruse J, Lewis R. Historical atlas of immunology. London: Taylor and Francis Group; 2005.CrossRefGoogle Scholar
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    Amico P, Hönger G, Mayr M, Steiger J, Hopfer H, Schaub S. Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads. Transplantation. 2009;87(11):1681–8.CrossRefGoogle Scholar
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    Pandey S, Rhodes-Clark B, Borja-Cacho D, Jethava Y, Harville T. P159 High-resolution HLA-typing can confirm diagnosis of graft versus host disease after orthotopic liver-transplantation. Hum Immunol. 2016;77:153.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory ServicesUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Departments of Pathology and Laboratory Services, Pediatrics, and Internal MedicineUniversity of Arkansas for Medical SciencesLittle RockUSA

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