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Acute Dyspnea After Platelet Transfusion

  • Laura CoolingEmail author
Chapter

Abstract

  • Transfusion-associated lung injury (TRALI) is defined as the onset of acute, non-cardiogenic pulmonary edema within 6 h of transfusion and the absence of pre-existing acute lung injury

  • Diagnostic findings are hypoxia (O2 saturation < 90% in room air), a PaO2/FiO2 ratio < 300 mmHg and new bilateral pulmonary infiltrates.

  • With O2 supplementation, up to 72% of cases of TRALI resolve within 48–96 h

  • High dose steroids have no benefit in TRALI

Keywords

Transfusion-associated lung injury Pulmonary edema Acute lung injury FiO2 

References

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of PathologyUniversity of MichiganAnn ArborUSA

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