Nonalcoholic Steatohepatitis Referred for Liver Transplantation

  • Laura CoolingEmail author


  • Individuals with severe IgA deficiency (IgA < 0.05 mg/dL) are at risk for severe allergic reactions and anaphylaxis, due to the presence of pre-formed circulating IgE anti-IgA auto antibodies

  • Up to one fifth of all anaphylactic transfusion reactions are due to severe IgA deficiency

  • Testing for severe IgA deficiency and anti-IgA antibodies can be done through ELISA and agglutination-based assays

  • Autologous blood donation might be an option for minor, non-urgent, scheduled procedures in patients with selective IgA deficiency


Non-alcoholic steatohepatitis IgA deficiency Anaphylaxis Autologous blood donation 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of PathologyUniversity of MichiganAnn ArborUSA

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