Neck Stiffness and Fever

  • Tangie Ngek Larry
  • Derrick Tembi Efie


  • Tuberculosis (TB) meningitis is an infection of the meninges of the brain caused by the bacteria Mycobacterium tuberculosis

  • Up to 20% of patients with TB meningitis have no meningismus signs

  • Xpert gene MTB/RIF is a rapid and sensitive way of detecting microbiologically proven TB meningitis with a high sensitivity


Tuberculosis meningitis Isoniazid Rifampicin Pyrazinamide Ethambutol 


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    Chin JH. Tuberculous meningitis. Neurol Clin Pract. 2004;4(3):199–205.CrossRefGoogle Scholar
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    Harman R. Handbook of pharmacy healthcare: diseases and patient advice. 2nd ed. London: Pharmaceutical Press; 2002.Google Scholar
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    Patel VB, Theron G, Lenders L, Matinyena B, Connolly C, Singh R, Coovadia Y, Ndung’u T, Dheda K. Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study. PLoS Med. 2013;10(10):e1001536.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Tangie Ngek Larry
    • 1
  • Derrick Tembi Efie
    • 2
    • 3
  1. 1.Faculty of Medicine and Biomedical SciencesUniversity of Yaounde 1YaoundeCameroon
  2. 2.Tokombere District HospitalTokombereCameroon
  3. 3.Health and Human Development Research NetworkDoualaCameroon

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