A Research Wish List to Understand, Diagnose, and Manage Frailty and Sarcopenia

  • Michael A. DunnEmail author


Loss of muscle mass and function in advanced liver disease has become a topic of rapidly growing interest since reports relating frailty and sarcopenia to risk of adverse liver transplant outcomes began to appear 7 years ago. Our current rapid growth in understanding of the problem has allowed the emergence of robust new opportunities for basic and clinical research that promise to improve the outcomes and quality of life of patients with cirrhosis.


Sarcopenia Cirrhosis Frailty Proteostasis Ammonia 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Center for Liver Diseases, Thomas E. Starzl Transplantation InstitutePittsburghUSA
  2. 2.Pittsburgh Liver Research Center, University of PittsburghPittsburghUSA

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