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Outcomes of Pregnancy After Transplantation: National Transplant Pregnancy Registry

  • Lisa A. Coscia
  • Dawn Armenti
  • Serban Constantinescu
  • Michael J. MoritzEmail author
Chapter

Abstract

The National Transplant Pregnancy Registry (NTPR) was established in 1991 to study outcomes of pregnancy after transplantation, including female recipients who have had pregnancies including those pregnancies fathered by male transplant recipients. The NTPR collects data regarding pregnancy outcomes in all types of solid-organ transplant recipients, of which the kidney cohort is the largest. Eligible participants are identified to the NTPR by their healthcare providers, or they may self-enroll. The study is IRB-approved, and the informed consent allows for interviews with the recipients and their healthcare providers, as well as review of parent and child medical records. Data collected include health and medication history, transplant information, pregnancy outcome, and postpartum data. Long-term periodic follow-up of maternal and child health is also conducted.

Keywords

Kidney transplantation in pregnancy High-risk pregnancy Prenatal birth defects Pregnancy registry Kidney transplant recipient of childbearing age Immunosuppressive agents and pregnancy Pregnancy and immunosuppressive agents in transplantation Pregnancy after retransplantation Pregnancies fathered by kidney transplant recipients National transplant pregnancy registry 

Notes

Acknowledgment

The NTPR acknowledges the cooperation of transplant recipients and the healthcare professionals in over 250 transplant centers in North America who have contributed their time and information to the NTPR. The NTPR is supported by grants from Astellas Pharma US, Inc., Pfizer Inc., and Bristol-Myers Squibb Company and contributions from other members of the transplant community.

In Memoriam

This manuscript is dedicated to Vincent T. Armenti, MD, PhD (1952–2014), the founder and principal investigator of the NTPR. His guidance and leadership allowed the NTPR to flourish and provide countless transplant recipients with scientific-based information from which to base their family planning decisions.

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Lisa A. Coscia
    • 1
  • Dawn Armenti
    • 1
  • Serban Constantinescu
    • 1
    • 2
  • Michael J. Moritz
    • 1
    • 3
    • 4
    Email author
  1. 1.Transplant Pregnancy Registry International (TPR)Gift of Life InstitutePhiladelphiaUSA
  2. 2.Kidney Transplant Program, Section of Nephrology, Hypertension and Kidney TransplantationLewis Katz School of Medicine, Temple UniversityPhiladelphiaUSA
  3. 3.Transplant ServicesLehigh Valley HospitalAllentownUSA
  4. 4.Department of SurgeryUniversity of South Florida, Morsani College of MedicineTampaUSA

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