There are three pairs of major salivary glands and several hundred minor salivary glands. The parotid gland is made up of serous-type acini with the exception of a few mucinous units; the submandibular gland is mixed with a predominance of serous-type acini; and the sublingual gland is predominantly composed of mucinous-type acini. Many lesions can arise or involve the salivary glands, including non-neoplastic lesions, primary benign and malignant neoplasms, and metastatic malignancies. Fine-needle aspiration (FNA) has been accepted as an excellent although challenging method of evaluating salivary gland lesions with very good sensitivity, specificity, and accuracy. A number of reporting schemes have been utilized, with the Milan System being the latest international effort aimed at standardizing the reporting of salivary gland cytopathology in order to facilitate appropriate clinical management.
KeywordsSalivary gland Adenoid cystic carcinoma Pleomorphic adenoma Warthin tumor Mucoepidermoid carcinoma Acinic cell carcinoma
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