Current Therapeutics for Cardiac Disease

  • Abdallah Al-MohammadEmail author


The past few decades have witnessed a revolution in the knowledge gained on cardiovascular disease treatment and prevention, providing us with one of the best evidence-bases in medicine. This chapter provides the reader with the basis for understanding the mechanisms of action, clinical uses and toxicity of the drugs used in the prevention and therapy of cardiovascular diseases. There is also some coverage of the adverse cardiovascular effects of drugs used for the treatment of diseases in other organ systems. The understanding of these drugs will assist the pathologists in their interpretation of clinical cases and to provide more insightful clinical advice based on knowledge of drug action.


Antihypertensives Antiarrhythmics Lipid lowering Acute coronary syndrome Heart failure Antiplatelet drugs Toxicity 

Further Reading

  1. Brunton LL, Hilal-Dandan R, Knollmann BC. Goodman and Gilman’s the pharmacological basis of therapeutics. 13th ed. New York, NY: McGraw-Hill; 2018.Google Scholar
  2. Camm AJ, Luscher TF, Maurer G, Serruys PW. ESC CardioMed. 3rd ed. Oxford: Oxford University Press; 2018.Google Scholar
  3. Fox K, Garcia MA, Ardissino D, Uszman P, et al. Guidelines in the management of stable angina pectoris: executive summary: the task force on the management of stable angina pectoris of the European Society of Cardiology. Eur Heart J. 2006;27:1341–81.CrossRefGoogle Scholar
  4. McInnes GT. Clinical pharmacology and therapeutics of hypertension. Volume 25 of handbook of hypertension. Amsterdam: Elsevier; 2008.Google Scholar
  5. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016;37:2129–200.CrossRefGoogle Scholar
  6. Toth PP. Drug treatment of hyperlipidaemia: a guide to the rational use of lipid-lowering drugs. Drugs. 2010;70:1363–79.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Cardiology Department, Chesterman WingNorthern General HospitalSheffieldUK

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