Liver Diseases pp 715-720 | Cite as

Extracorporeal Non cellular Liver Assisted Devices

  • Mehul Shah
  • Nikolaos T. PyrsopoulosEmail author


Liver Failure is associated with high mortality, whether it is an acute liver failure or acute decompensation on chronic liver disorder. Liver transplantation has been deemed to be a life saving procedure for end stages of liver failure. Due to high demand of liver grafts and limited availability there are instances where there is a need to bridge the gap until a graft is available. This chapter elaborates the currently available extracorporeal non cellular liver assist devices that includes Molecular adsorbent recirculating system (MARS), Prometheus—Fractionated plasma separation and adsorption system (FSPA), Single pass albumin dialysis (SPAD), and Selective plasma filtration therapy (SEPET) in an effort to support patients with end stages liver failure until a graft will become available or facilitate regeneration.


Acute on chronic live failure Acute liver failure Artificial liver support Non cellular liver support assisted devices Albumin dialysis MARS Prometheus SPAD FPSA 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Division of Gastroenterology and HepatologyRutgers—New Jersey Medical SchoolNewarkUSA

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