Liver Diseases pp 533-543 | Cite as

Contrast Enhanced MR imaging of Liver

  • Ran-Chou Chen
  • Chen-Te Chou
  • Yung-Liang Wan


Contrast enhanced dynamic MRI is one of the best noninvasive imaging modalities in diagnosis of liver lesions. Recent progress of the MR scanner, software techniques and new contrast agents have increased the effectiveness and accuracy in detecting and characterizing liver disease, especially focal hepatic lesions.

Currently, the extracellular contrast agent Gd-DTPA and the combined agent Gd-EOB-DTPA are the most frequently used contrast media in clinical practice. The diagnosis of hepatocellular carcinoma could be established by the typical arterial enhancement and washout phenomenon in the venous/delayed phases. Furthermore, Gd-EOB-DTPA provides quantitative functional information, help in staging liver fibrosis and provide additional tumor information in hepatobiliary images. Therefore, the contrast enhanced MR is widely used in the diagnosis of diffuse liver disease and focal hepatic lesions. However, future studies are still needed to continuously improve the diagnostic accuracy.


Gd-DTPA Gd-EOB-DTPA Contrast enhanced dynamic MR FNH HCC 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Ran-Chou Chen
    • 1
    • 2
  • Chen-Te Chou
    • 2
    • 3
    • 4
    • 5
  • Yung-Liang Wan
    • 6
    • 7
  1. 1.Commissioner, Department of HealthNew Taipei City GovernmentNew Taipei CityTaiwan
  2. 2.Department of Biomedical Imaging and Radiological SciencesNational Yang-Ming UniversityTaipei CityTaiwan
  3. 3.Department of RadiologyChanghua Christian HospitalChanghua CityTaiwan
  4. 4.School of MedicineKaohsiung Medical UniversityKaohsiungTaiwan
  5. 5.Department of Molecular Biotechnology, College of Biotechnology and BioresourcesDayeh UniversityChanghua CityTaiwan
  6. 6.Department of Medical Imaging and Radiological Sciences, College of MedicineChang Gung UniversityTaoyuan CityTaiwan
  7. 7.Department of Medical Imaging and InterventionLinkou Chang Gung Memorial HospitalTaoyuan CityTaiwan

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