Liver Diseases pp 143-151 | Cite as

Autoimmune Hepatitis

  • Christos Liaskos
  • George Efthymiou
  • Dimitrios P. BogdanosEmail author


Autoimmune hepatitis (AIH) is a relatively rare autoimmune liver disease of unknown aetiology. The disease is characterized by immune-mediated destruction of the hepatocytes and progressive inflammation and subsequent liver fibrosis leading to organ’s failure, if the disease is left untreated. Genetic, epigenetic and immunological factors are considered important for the development of the disease.


Antibody Autoantibody Autoantigen Autoimmunity Clinician Disease Hepatitis Liver Autoimmune liver disease Corticosteroids 



Autoimmune hepatitis


Anti-mitochondrial antibody


Liver cytosol type 1


Liver kidney microsomal type 1


Perinuclear antineutrophil cytoplasmic antibodies


Smooth muscle antibody


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Christos Liaskos
    • 1
  • George Efthymiou
    • 1
  • Dimitrios P. Bogdanos
    • 1
    Email author
  1. 1.Division of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health SciencesUniversity of ThessalyLarissaGreece

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