Liver Diseases pp 117-128 | Cite as

Vascular Disorders of the Liver

  • Vlad Damian Vintilă
  • Alexandra Maria Chitroceanu
  • Ana-Maria Vintilă


The liver has a complex vascular system, with a dual blood supply divided between the hepatic artery and the portal vein, which ultimately mixes within the hepatic sinusoids before draining into the systemic circulation via the hepatic venous system. Each of its components can be damaged by various types of injury. Vascular disorders of the liver are rare conditions, usually affecting young people, with high morbidity and mortality that can occur in the absence of a proper diagnosis and disease-specific management. In the last years, international collaborations provided data-supported approaches, which allowed to increase knowledge and awareness in understanding and management of these conditions. Given the rarity of some vascular disorders of the liver, not all will be discussed in this chapter. Definition, aetiology, diagnosis, treatment and prognosis of the most common vascular disorders of the liver will be considered. Moreover morphological and functional changes relevant to the clinical aspect are explained.


Hepatic venous outflow tract obstruction Budd-Chiari syndrome Portal vein thrombosis Portal cavernoma Nodular regenerative hyperplasia Sinusoidal obstruction syndrome Congenital vascular malformations of the liver Hereditary haemorrhagic telangiectasia Congenital arteriovenous shunt Congenital arterioportal shunt Congenital portosystemic shunt 



Budd-Chiari syndrome


Hepatic venous outflow tract


Portal vein thrombosis


Sinusoidal obstruction syndrome


Veno-occlusive disease


Hereditary haemorrhagic telangiectasia


Magnetic resonance angiography


Computed tomography angiography


Transjugular intrahepatic portosystemic shunt


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Vlad Damian Vintilă
    • 1
    • 2
    • 3
  • Alexandra Maria Chitroceanu
    • 4
  • Ana-Maria Vintilă
    • 1
    • 5
  1. 1.Carol Davila University of Medicine and PharmacyBucharestRomania
  2. 2.University of Medicine and Pharmacy, University Emergency HospitalBucharestRomania
  3. 3.Department of CardiologyEmergency University HospitalBucharestRomania
  4. 4.Department of CardiologyUniversity and Emergency HospitalBucharestRomania
  5. 5.Department of Internal Medicine and CardiologyColțea Clinical HospitalBucharestRomania

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