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Renal Cancer pp 221-242 | Cite as

Open Partial Nephrectomy

  • Marianne M. Casilla-Lennon
  • Patrick A. Kenney
  • Matthew Wszolek
  • John A. Libertino
Chapter

Abstract

Open partial nephrectomy (PN) is a challenging operation that requires complete tumor resection with a negative margin and maximal preservation of functioning renal parenchyma with the aim of maximizing cancer-specific survival and minimizing postoperative chronic kidney disease, morbidity, and mortality. This chapter provides a detailed discussion of the rationale for PN as well as its current indications. The importance of minimizing renal ischemia and other predictors of postoperative CKD is discussed. The techniques of open PN are described.

Keywords

Open partial nephrectomy Nephron-sparing surgery Renal cell carcinoma Technique Complications Ischemia 

Supplementary material

Video 13.1

(MPG 18955 kb)

References

  1. 1.
    Campbell S, Uzzo RG, Allaf ME, Bass EB, Cadeddu JA, Chang A, et al. Renal mass and localized renal cancer: AUA guideline. J Urol. 2017;198(3):520–9.CrossRefGoogle Scholar
  2. 2.
    Ljungberg B, Bensalah K, Canfield S, Dabestani S, Hofmann F, Hora M, et al. EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol. 2015;67(5):913–24.CrossRefGoogle Scholar
  3. 3.
    Herr H. A history of partial nephrectomy for renal tumors. J Urol. 2005;173(3):705–8.CrossRefPubMedGoogle Scholar
  4. 4.
    Herr HW. Surgical management of renal tumors: a historical perspective. Urol Clin North Am. 2008;35(4):543–9.CrossRefPubMedGoogle Scholar
  5. 5.
    Bell E. A classification of renal tumors with observations on the frequency of the various types. J Urol. 1938;39:238.CrossRefGoogle Scholar
  6. 6.
    Vermooten V. Indications for conservative surgery in certain renal tumors: a study based on the growth pattern of the cell carcinoma. J Urol. 1950;64(2):200–8.CrossRefPubMedGoogle Scholar
  7. 7.
    Zinman L, Dowd JB. Partial nephrectomy in renal cell carcinoma. Surg Clin North Am. 1967;47(3):685–93.CrossRefPubMedGoogle Scholar
  8. 8.
    WICKHAM JEA. Conservative renal surgery for adenocarcinoma. The place of bench surgery. Br J Urol. 1975;47(1):25–36.CrossRefPubMedGoogle Scholar
  9. 9.
    Licht MR, Novick AC. Nephron sparing surgery for renal cell carcinoma. J Urol. 1993;149(1):1–7.CrossRefPubMedGoogle Scholar
  10. 10.
    Herr HW. Partial nephrectomy for unilateral renal carcinoma and a normal contralateral kidney: 10-year followup. J Urol. 1999;161(1):33–5.CrossRefPubMedGoogle Scholar
  11. 11.
    Fergany AFA, Hafez KSK, Novick ACA. Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup. J Urol. 2000;163(2):442–5.CrossRefPubMedGoogle Scholar
  12. 12.
    Huang WC, Levey AS, Serio AM, Snyder M, Vickers AJ, Raj GV, et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol. 2006;7(9):735–40.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Huang WC, Elkin EB, Levey AS, Jang TL, Russo P. Partial nephrectomy versus radical nephrectomy in patients with small renal tumors--is there a difference in mortality and cardiovascular outcomes? J Urol. 2009;181(1):55–61; discussion 61–2.CrossRefPubMedGoogle Scholar
  14. 14.
    Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN. Int J Cancer. 2012;136(5):E359–86.CrossRefGoogle Scholar
  15. 15.
    Siegel R, Miller K, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30.CrossRefGoogle Scholar
  16. 16.
    Chow W-H, Dong LM, Devesa SS. Epidemiology and risk factors for kidney cancer. Nat Publ Group. 2010;7(5):13.Google Scholar
  17. 17.
    Storkel S, Eble JN, Adlakha K, Amin M, Blute ML, Bostwick DG, et al. Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer. 1997;80(5):987–9.CrossRefPubMedGoogle Scholar
  18. 18.
    Chow W-H, Devesa SS. Contemporary epidemiology of renal cell cancer. Cancer J. 2008;14(5):288–301.CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, et al. Cancer incidence in five continents. Lyon: International Agency for Research on Cancer; 2007.Google Scholar
  20. 20.
    Hunt JD, van der Hel OL, McMillan GP, Boffetta P. Renal cell carcinoma in relation to cigarette smoking: meta-analysis of 24 studies. Int J Cancer. 2005;114(1):101–8.CrossRefPubMedGoogle Scholar
  21. 21.
    Chow WH, Gridley G, Fraumeni JF, Järvholm B. Obesity, hypertension, and the risk of kidney cancer in men. N Engl J Med. 2000;343(18):1305–11.CrossRefPubMedGoogle Scholar
  22. 22.
    Pischon T, Lahmann PH, Boeing H, Tjønneland A, Halkjaer J, Overvad K, et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer. 2006;118(3):728–38.CrossRefPubMedGoogle Scholar
  23. 23.
    Oh SW, Yoon YS, Shin S-A. Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study. J Clin Oncol. 2005;23(21):4742–54.CrossRefPubMedGoogle Scholar
  24. 24.
    Levi F, Ferlay J, Galeone C, Lucchini F, Negri E, Boyle P, et al. The changing pattern of kidney cancer incidence and mortality in Europe. BJU Int. 2008;101(8):949–58.CrossRefPubMedGoogle Scholar
  25. 25.
    Kane CJ, Mallin K, Ritchey J, Cooperberg MR, Carroll PR. Renal cell cancer stage migration: analysis of the National Cancer Data Base. Cancer. 2008;113(1):78–83.CrossRefGoogle Scholar
  26. 26.
    Cooperberg MR, Mallin K, Ritchey J, Villalta JD, Carroll PR, Kane CJ. Decreasing size at diagnosis of stage 1 renal cell carcinoma: analysis from the National Cancer Data Base, 1993 to 2004. J Urol. 2008;179(6):2131–5.CrossRefPubMedGoogle Scholar
  27. 27.
    FRANK I, Blute ML, CHEVILLE JC, Lohse CM, WEAVER AL, ZINCKE H. Solid renal tumors: an analysis of pathological features related to tumor size. J Urol. 2003;170(6 Pt 1):2217–20.CrossRefPubMedGoogle Scholar
  28. 28.
    Remzi M, Ozsoy M, Klingler H-C, Susani M, Waldert M, Seitz C, et al. Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter. J Urol. 2006;176(3):896–9.CrossRefPubMedGoogle Scholar
  29. 29.
    Pahernik S, Ziegler S, Roos F, Melchior SW, Thüroff JW. Small renal tumors: correlation of clinical and pathological features with tumor size. J Urol. 2007;178(2):414–7; discussion 416–7.CrossRefPubMedGoogle Scholar
  30. 30.
    Nguyen MM, Gill IS. Effect of renal cancer size on the prevalence of metastasis at diagnosis and mortality. J Urol. 2009;181(3):8.CrossRefGoogle Scholar
  31. 31.
    Thompson RH, Hill JR, Babayev Y, Cronin A, Kaag M, Kundu S, et al. Metastatic renal cell carcinoma risk according to tumor size. J Urol. 2009;182(1):41–5.CrossRefPubMedPubMedCentralGoogle Scholar
  32. 32.
    Lau WK, Blute ML, Weaver AL, Torres VE, Zincke H. Matched comparison of radical nephrectomy vs nephron-sparing surgery in patients with unilateral renal cell carcinoma and a normal contralateral kidney. Mayo Clin Proc. 2000;75(12):1236–42.CrossRefPubMedGoogle Scholar
  33. 33.
    van Poppel H, Da Pozzo L, Albrecht W, Matveev V, Bono A, Borkowski A, et al. A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol. 2011;59(4):543–52.CrossRefPubMedGoogle Scholar
  34. 34.
    Crépel M, Jeldres C, Sun M, Lughezzani G, Isbarn H, Alasker A, et al. A population-based comparison of cancer-control rates between radical and partial nephrectomy for T1A renal cell carcinoma. Urology. 2010;76(4):883–8.CrossRefPubMedGoogle Scholar
  35. 35.
    Patard J-J, Shvarts O, Lam JS, Pantuck AJ, Kim HL, Ficarra V, et al. Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. J Urol. 2004;171(6 Pt 1):2181–5; quiz 2435.CrossRefPubMedGoogle Scholar
  36. 36.
    Antonelli A, Cozzoli A, Nicolai M, Zani D, Zanotelli T, Perucchini L, et al. Nephron-sparing surgery versus radical nephrectomy in the treatment of intracapsular renal cell carcinoma up to 7cm. Eur Urol. 2008;53(4):7.CrossRefGoogle Scholar
  37. 37.
    Lee CT, Katz J, Shi W, Thaler HT, Reuter VE, Russo P. Surgical management of renal tumors 4 cm. or less in a contemporary cohort. J Urol. 2000;163(3):730–6.CrossRefPubMedGoogle Scholar
  38. 38.
    Crépel M, Jeldres C, Perrotte P, Capitanio U, Isbarn H, Shariat SF, et al. Nephron-sparing surgery is equally effective to radical nephrectomy for T1BN0M0 renal cell carcinoma: a population-based assessment. Urology. 2010;75(2):271–5.CrossRefPubMedGoogle Scholar
  39. 39.
    Weight CJ, Larson BT, Gao T, Campbell SC, Lane BR, Kaouk JH, et al. Elective partial nephrectomy in patients with clinical T1b renal tumors is associated with improved overall survival. Urology. 2010;76(3):631–7.CrossRefPubMedGoogle Scholar
  40. 40.
    Joniau S, Vander Eeckt K, Srirangam SJ, Van Poppel H. Outcome of nephron-sparing surgery for T1b renal cell carcinoma. BJU Int. 2009;103(10):1344–8.CrossRefPubMedGoogle Scholar
  41. 41.
    Pahernik S, Roos F, Röhrig B, Wiesner C, Thüroff JW. Elective nephron sparing surgery for renal cell carcinoma larger than 4 cm. J Urol. 2008;179(1):71–4; discussion 74.CrossRefPubMedGoogle Scholar
  42. 42.
    Thompson RH, Siddiqui S, Lohse CM, Leibovich BC, Russo P, Blute ML. Partial versus radical nephrectomy for 4 to 7 cm renal cortical tumors. J Urol. 2009;182(6):2601–6.CrossRefPubMedPubMedCentralGoogle Scholar
  43. 43.
    Margulis V, Tamboli P, Jacobsohn KM, Swanson DA, Wood CG. Oncological efficacy and safety of nephron-sparing surgery for selected patients with locally advanced renal cell carcinoma. BJU Int. 2007;100(6):1235–9.CrossRefPubMedGoogle Scholar
  44. 44.
    Breau RH, Crispen PL, Jimenez RE, Lohse CM, Blute ML, Leibovich BC. Outcome of stage T2 or greater renal cell cancer treated with partial nephrectomy. J Urol. 2010;183(3):903–8.CrossRefPubMedGoogle Scholar
  45. 45.
    Karellas ME, O’Brien MF, Jang TL, Bernstein M, Russo P. Partial nephrectomy for selected renal cortical tumours of ≥ 7 cm. BJU Int. 2010;106(10):1484–7.CrossRefPubMedPubMedCentralGoogle Scholar
  46. 46.
    Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C-Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351(13):1296–305.CrossRefPubMedPubMedCentralGoogle Scholar
  47. 47.
    Ramcharan T, Matas AJ. Long-term (20-37 years) follow-up of living kidney donors. Am J Transplant. 2002;2(10):959–64.CrossRefPubMedGoogle Scholar
  48. 48.
    Okamoto MM, Akioka KK, Nobori SS, Ushigome HH, Kozaki KK, Kaihara SS, et al. Short- and long-term donor outcomes after kidney donation: analysis of 601 cases over a 35-year period at Japanese single center. Transplantation. 2009;87(3):419–23.CrossRefPubMedGoogle Scholar
  49. 49.
    Najarian JSJ, Chavers BMB, McHugh LEL, Matas AJA. 20 years or more of follow-up of living kidney donors. Lancet. 1992;340(8823):807–10.CrossRefPubMedGoogle Scholar
  50. 50.
    Wszolek MF, Kenney PA, Lee Y, Libertino JA. Comparison of hilar clamping and non-hilar clamping partial nephrectomy for tumours involving a solitary kidney. BJU Int. 2011;107(12):1886–92.CrossRefPubMedGoogle Scholar
  51. 51.
    La Rochelle J, Shuch B, Riggs S, Liang L-J, Saadat A, Kabbinavar F, et al. Functional and oncological outcomes of partial nephrectomy of solitary kidneys. J Urol. 2009;181(5):7.CrossRefGoogle Scholar
  52. 52.
    Bijol V, Mendez GP, Hurwitz S, Rennke HG, Nosé V. Evaluation of the nonneoplastic pathology in tumor nephrectomy specimens: predicting the risk of progressive renal failure. Am J Surg Pathol. 2006;30(5):575–84.CrossRefPubMedGoogle Scholar
  53. 53.
    Levey AS, Coresh J, Balk E, Kausz AT, Levin A, Steffes MW, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003;139(2):137–47.CrossRefPubMedGoogle Scholar
  54. 54.
    Foley RN, Wang C, Collins AJ. Cardiovascular risk factor profiles and kidney function stage in the US general population: the NHANES III study. Mayo Clin Proc. 2005;80(10):9.CrossRefGoogle Scholar
  55. 55.
    McKiernan J, Simmons R, Katz J, Russo P. Natural history of chronic renal insufficiency after partial and radical nephrectomy. Urology. 2002;59(6):816–20.CrossRefPubMedGoogle Scholar
  56. 56.
    Thompson RH, Boorjian SA, Lohse CM, Leibovich BC, Kwon ED, Cheville JC, et al. Radical nephrectomy for pT1a renal masses may be associated with decreased overall survival compared with partial nephrectomy. J Urol. 2008;179(2):468–71; discussion 472–3.CrossRefPubMedGoogle Scholar
  57. 57.
    Kim SP, Shah ND, Weight CJ, Thompson RH, Moriarty JP, Shippee ND, et al. Contemporary trends in nephrectomy for renal cell carcinoma in the United States: results from a population based cohort. J Urol. 2011;186(5):1779–85.CrossRefPubMedGoogle Scholar
  58. 58.
    Hollenbeck BK, Taub DA, Miller DC, Dunn RL, Wei JT. National utilization trends of partial nephrectomy for renal cell carcinoma: a case of underutilization? Urology. 2006;67(2):254–9.CrossRefPubMedGoogle Scholar
  59. 59.
    Fero K, Hamilton ZA, Bindayi A, Murphy JD, Derweesh IH. Utilization and quality outcomes of cT1a, cT1b and cT2a partial nephrectomy: analysis of the national cancer database. BJU Int. 2018;121:565–74.CrossRefPubMedGoogle Scholar
  60. 60.
    Dulabon LM, Lowrance WT, Russo P, Huang WC. Trends in renal tumor surgery delivery within the United States. Cancer. 2010;116(10):2316–21.PubMedPubMedCentralGoogle Scholar
  61. 61.
    Zini L, Patard JJ, Capitanio U, Mejean A, Villers A, La Taille de A, et al. The use of partial nephrectomy in European tertiary care centers. Eur J Surg Oncol. 2009;35(6):7.CrossRefGoogle Scholar
  62. 62.
    Thompson RH, Kaag M, Vickers A, Kundu S, Bernstein M, Lowrance W, et al. Contemporary use of partial nephrectomy at a tertiary care center in the United States. J Urol. 2009;181(3):993–7.CrossRefPubMedPubMedCentralGoogle Scholar
  63. 63.
    Patel HD, Mullins JK, Pierorazio PM, Jayram G, Cohen JE, Matlaga BR, et al. Trends in renal surgery: robotic technology is associated with increased use of partial nephrectomy. J Urol. 2013;189(4):1229–35.CrossRefPubMedGoogle Scholar
  64. 64.
    Link RE, Bhayani SB, Allaf ME, Varkarakis I, Inagaki T, Rogers C, et al. Exploring the learning curve, pathological outcomes and perioperative morbidity of laparoscopic partial nephrectomy performed for renal mass. J Urol. 2005;173(5):1690–4.CrossRefPubMedGoogle Scholar
  65. 65.
    Gill IS, Kavoussi LR, Lane BR, Blute ML, Babineau D, Colombo JR, et al. Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol. 2007;178(1):41–6.CrossRefPubMedGoogle Scholar
  66. 66.
    Tabayoyong W, Abouassaly R, Kiechle JE, Cherullo EE, Meropol NJ, Shah ND, et al. Variation in surgical margin status by surgical approach among patients undergoing partial nephrectomy for small renal masses. J Urol. 2015;194(6):1548–53.CrossRefPubMedGoogle Scholar
  67. 67.
    Maurice MJ, Zhu H, Kim SP, Abouassaly R. Increased use of partial nephrectomy to treat high-risk disease. BJU Int. 2016;117(6B):E75–86.CrossRefPubMedGoogle Scholar
  68. 68.
    Weight CJ, Crispen PL, Breau RH, Kim SP, Lohse CM, Boorjian SA, et al. Practice-setting and surgeon characteristics heavily influence the decision to perform partial nephrectomy among American Urologic Association surgeons. BJU Int [Internet]. 2013;111(5):731–8. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2012.11112.x/abstract.CrossRefGoogle Scholar
  69. 69.
    Kutikov A, Uzzo RG. The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol. 2009;182(3):844–53.CrossRefGoogle Scholar
  70. 70.
    Simmons MN, Ching CB, Samplaski MK, Park CH, Gill IS. Kidney tumor location measurement using the C index method. J Urol. 2010;183(5):1708–13.CrossRefPubMedGoogle Scholar
  71. 71.
    Ficarra V, Novara G, Secco S, Macchi V, Porzionato A, De Caro R, et al. Preoperative aspects and dimensions used for an anatomical (PADUA) classification of renal tumours in patients who are candidates for nephron-sparing surgery. Eur Urol. 2009;56(5):786–93.CrossRefPubMedGoogle Scholar
  72. 72.
    Broughton GJ, Clark PE, Barocas DA, Cookson MS, Smith JA, Herrell SD, et al. Tumour size, tumour complexity, and surgical approach are associated with nephrectomy type in small renal cortical tumours treated electively. BJU Int [Internet]. 2012;109(11):1607–13. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2011.10607.x/abstract.CrossRefGoogle Scholar
  73. 73.
    Canter D, Kutikov A, Manley B, Egleston B, Simhan J, Smaldone M, et al. Utility of the R.E.N.A.L. nephrometry scoring system in objectifying treatment decision-making of the enhancing renal mass. Urology [Internet]. 2011;78(5):1089–94. Available from: http://www.sciencedirect.com.ezproxyhost.library.tmc.edu/science/article/pii/S0090429511004353.CrossRefGoogle Scholar
  74. 74.
    Rosevear HM, Gellhaus PT, Lightfoot AJ, Kresowik TP, Joudi FN, Tracy CR. Utility of the RENAL nephrometry scoring system in the real world: predicting surgeon operative preference and complication risk. BJU Int [Internet]. 2012;109(5):700–5. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2011.10452.x/abstract.CrossRefGoogle Scholar
  75. 75.
    Waldert M, Waalkes S, Klatte T, Kuczyk MA, Weibl P, Schüller G, et al. External validation of the preoperative anatomical classification for prediction of complications related to nephron-sparing surgery. World J Urol [Internet]. 2010;28(4):531–5. Available from: http://www.springerlink.com.ezproxyhost.library.tmc.edu/content/7l2660p1144761q8/fulltext.pdf.CrossRefGoogle Scholar
  76. 76.
    Samplaski MK, Hernandez A, Gill IS, Simmons MN. C-index is associated with functional outcomes after laparoscopic partial nephrectomy. J Urol. 2010;184(6):2259–63.CrossRefPubMedGoogle Scholar
  77. 77.
    Altunrende F, Laydner H, Hernandez AV, Autorino R, Khanna R, White MA, et al. Correlation of the RENAL nephrometry score with warm ischemia time after robotic partial nephrectomy. World J Urol [Internet]. 2013;31(5):1165–9. Available from: http://www.springerlink.com.ezproxyhost.library.tmc.edu/content/7621231072217650/?MUD=MP.CrossRefGoogle Scholar
  78. 78.
    Simmons MN, Hillyer SP, Lee BH, Fergany AF, Kaouk J, Campbell SC. Nephrometry score is associated with volume loss and functional recovery after partial nephrectomy. J Urol. 2012;188(1):39–44.CrossRefPubMedGoogle Scholar
  79. 79.
    Simhan J, Smaldone MC, Tsai KJ, Canter DJ, Li T, Kutikov A, et al. Objective measures of renal mass anatomic complexity predict rates of major complications following partial nephrectomy. Eur Urol. 2011;60(4):724–30.CrossRefPubMedPubMedCentralGoogle Scholar
  80. 80.
    Bruner B, Breau RH, Lohse CM, Leibovich BC, Blute ML. Renal nephrometry score is associated with urine leak after partial nephrectomy. BJU Int. 2011;108(1):67–72.CrossRefPubMedGoogle Scholar
  81. 81.
    Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007;116(17):e418–99.PubMedGoogle Scholar
  82. 82.
    Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100(10):1043–9.CrossRefPubMedGoogle Scholar
  83. 83.
    Bapoje SR, Whitaker JF, Schulz T, Chu ES, Albert RK. Preoperative evaluation of the patient with pulmonary disease. Chest. 2007;132(5):1637–45.CrossRefPubMedGoogle Scholar
  84. 84.
    Qaseem A, Snow V, Fitterman N, Hornbake ER, Lawrence VA, Smetana GW, et al. Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: a guideline from the American College of Physicians. Ann Intern Med. 2006;144(8):575–80.CrossRefPubMedGoogle Scholar
  85. 85.
    Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461–70.CrossRefGoogle Scholar
  86. 86.
    Coll DM, Uzzo RG, Herts BR, Davros WJ, Wirth SL, Novick AC. 3-dimensional volume rendered computerized tomography for preoperative evaluation and intraoperative treatment of patients undergoing nephron sparing surgery. J Urol. 1999;161(4):1097–102.CrossRefPubMedGoogle Scholar
  87. 87.
    Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 Suppl):381S–453S.CrossRefPubMedGoogle Scholar
  88. 88.
    Forrest JB, Clemens JQ, Finamore P, Leveillee R, Lippert M, Pisters L, et al. AUA Best Practice Statement for the prevention of deep vein thrombosis in patients undergoing urologic surgery. J Urol. 2009;181(3):1170–7.CrossRefPubMedGoogle Scholar
  89. 89.
    Kenney PA, Wotkowicz C, Libertino JA. Contemporary open surgery of the kidney. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Campbell-Walsh urology. 10th ed. Philadelphia: Saunders; 2011. p. 1554–627.Google Scholar
  90. 90.
    Turner Warwick RT. The supracostal approach to the renal area. Br J Urol. 1965;37(6):671–2.CrossRefPubMedGoogle Scholar
  91. 91.
    DiBlasio CJ, Snyder ME, Russo P. Mini-flank supra-11th rib incision for open partial or radical nephrectomy. BJU Int. 2006;97(1):149–56.CrossRefPubMedGoogle Scholar
  92. 92.
    Simmons MN, Schreiber MJ, Gill IS. Surgical renal ischemia: a contemporary overview. J Urol. 2008;180(1):19–30.CrossRefPubMedGoogle Scholar
  93. 93.
    Becker F, Van Poppel H, Hakenberg OW, Stief C, Gill I, Guazzoni G, et al. Assessing the impact of ischaemia time during partial nephrectomy. Eur Urol. 2009;56(4):625–34.CrossRefPubMedGoogle Scholar
  94. 94.
    Novick AC. Renal hypothermia: in vivo and ex vivo. Urol Clin North Am. 1983;10(4):637–44.PubMedGoogle Scholar
  95. 95.
    Power NE, Maschino AC, Savage C, Silberstein JL, Thorner D, Tarin T, et al. Intraoperative mannitol use does not improve long-term renal function outcomes after minimally invasive partial nephrectomy. Urology. 2012;79(4):821–5.CrossRefPubMedPubMedCentralGoogle Scholar
  96. 96.
    Spaliviero M, Power NE, Murray KS, Sjoberg DD, Benfante NE, Bernstein ML, et al. Intravenous mannitol versus placebo during partial nephrectomy in patients with normal kidney function: a double-blind, clinically-integrated, randomized trial. Eur Urol. 2018;73(1):53–9.CrossRefPubMedGoogle Scholar
  97. 97.
    Clark MA, Shikanov S, Raman JD, Smith B, Kaag M, Russo P, et al. Chronic kidney disease before and after partial nephrectomy. J Urol. 2011;185(1):43–8.CrossRefPubMedGoogle Scholar
  98. 98.
    Gong EM, Zorn KC, Orvieto MA, Lucioni A, Msezane LP, Shalhav AL. Artery-only occlusion may provide superior renal preservation during laparoscopic partial nephrectomy. Urology. 2008;72(4):843–6.CrossRefPubMedGoogle Scholar
  99. 99.
    Tracy CR, Terrell JD, Francis RP, Wehner EF, Smith J, Litorja M, et al. Characterization of renal ischemia using DLP hyperspectral imaging: a pilot study comparing artery-only occlusion versus artery and vein occlusion. J Endourol. 2010;24(3):321–5.CrossRefPubMedGoogle Scholar
  100. 100.
    Thompson RH, FRANK I, Lohse CM, Saad IR, Fergany A, ZINCKE H, et al. The impact of ischemia time during open nephron sparing surgery on solitary kidneys: a multi-institutional study. J Urol. 2007;177(2):471–6.CrossRefPubMedGoogle Scholar
  101. 101.
    Thompson RH, Lane BR, Lohse CM, Leibovich BC, Fergany A, FRANK I, et al. Every minute counts when the renal hilum is clamped during partial nephrectomy. Eur Urol. 2010;58(3):340–5.CrossRefPubMedGoogle Scholar
  102. 102.
    Gill IS, Eisenberg MS, Aron M, Berger A, Ukimura O, Patil MB, et al. “Zero ischemia” partial nephrectomy: novel laparoscopic and robotic technique. Eur Urol. 2011;59(1):128–34.CrossRefPubMedGoogle Scholar
  103. 103.
    Walther MM, Thompson N, Linehan W. Enucleation procedures in patients with multiple hereditary renal tumors. World J Urol. 1995;13(4):248–50.CrossRefPubMedGoogle Scholar
  104. 104.
    Li QL, Guan HW, Zhang QP, Zhang LZ, Wang FP. Optimal margin in nephron-sparing surgery for renal cell carcinoma 4 cm or less. Eur Urol. 2003;44:448.CrossRefPubMedGoogle Scholar
  105. 105.
    Blackley SK, Ladaga L, Woolfitt RA, Schellhammer PF. Ex situ study of the effectiveness of enucleation in patients with renal cell carcinoma. J Urol. 1988;140(1):6–10.CrossRefPubMedGoogle Scholar
  106. 106.
    Marshall FF, Taxy JB, Fishman EK, Chang R. The feasibility of surgical enucleation for renal cell carcinoma. J Urol. 1986;135(2):231–4.CrossRefPubMedGoogle Scholar
  107. 107.
    Rosenthal CL, Kraft R, Zingg EJ. Organ-preserving surgery in renal cell carcinoma: tumor enucleation versus partial kidney resection. Eur Urol. 1984;10(4):222–8.CrossRefPubMedGoogle Scholar
  108. 108.
    Kutikov A, Vanarsdalen KN, Gershman B, Fossett LK, Guzzo TJ, Wein AJ, et al. Enucleation of renal cell carcinoma with ablation of the tumour base. BJU Int. 2008;102(6):688–91.CrossRefPubMedGoogle Scholar
  109. 109.
    Assimos DG, Boyce H, Woodruff RD, Harrison LH, McCullough DL, Kroovand RL. Intraoperative renal ultrasonography: a useful adjunct to partial nephrectomy. J Urol. 1991;146(5):1218–20.CrossRefPubMedGoogle Scholar
  110. 110.
    Campbell SC, Fichtner J, Novick AC, Steinbach F, Stöckle M, Klein EA, et al. Intraoperative evaluation of renal cell carcinoma: a prospective study of the role of ultrasonography and histopathological frozen sections. J Urol. 1996;155(4):1191–5.CrossRefPubMedGoogle Scholar
  111. 111.
    Castilla EA, Liou LS, Abrahams NA, Fergany A, Rybicki LA, Myles J, et al. Prognostic importance of resection margin width after nephron-sparing surgery for renal cell carcinoma. Urology. 2002;60(6):993–7.CrossRefPubMedGoogle Scholar
  112. 112.
    Godoy G, Katz DJ, Adamy A, Jamal JE, Bernstein M, Russo P. Routine drain placement after partial nephrectomy is not always necessary. J Urol. 2011;186(2):411–6.CrossRefPubMedGoogle Scholar
  113. 113.
    Lane BR, Babineau DC, Poggio ED, Weight CJ, Larson BT, Gill IS, et al. Factors predicting renal functional outcome after partial nephrectomy. J Urol. 2008;180(6):2363–8; discussion 2368–9.CrossRefPubMedGoogle Scholar
  114. 114.
    Lane BR, Russo P, Uzzo RG, Hernandez AV, Boorjian SA, Thompson RH, et al. Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function. J Urol. 2011;185(2):421–7.CrossRefPubMedGoogle Scholar
  115. 115.
    Russo P. Partial nephrectomy for renal cancer (part II): the impact of renal ischaemia, patient preparation, surgical approaches, management of complications and utilization. BJU Int. 2010;105(11):1494–507.CrossRefPubMedGoogle Scholar
  116. 116.
    Thompson RH, Lane BR, Lohse CM, Leibovich BC, Fergany A, FRANK I, et al. Renal function after partial nephrectomy: effect of warm ischemia relative to quantity and quality of preserved kidney. Urology. 2012;79(2):356–60.CrossRefPubMedGoogle Scholar
  117. 117.
    Smith GL, Kenney PA, Lee Y, Libertino JA. Non-clamped partial nephrectomy: techniques and surgical outcomes. BJU Int. 2011;107(7):1054–8.CrossRefPubMedGoogle Scholar
  118. 118.
    Wszolek MF, Kenney PA, Libertino JA. Nonclamping partial nephrectomy: towards improved nephron sparing. Nat Rev Urol. 2011;8(9):523–7.CrossRefPubMedGoogle Scholar
  119. 119.
    Rais-Bahrami S, George AK, Herati AS, Srinivasan AK, Richstone L, Kavoussi LR. Off-clamp versus complete hilar control laparoscopic partial nephrectomy: comparison by clinical stage. BJU Int. 2012;109(9):1376–81.CrossRefPubMedGoogle Scholar
  120. 120.
    Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A, editors. AJCC Cancer Staging Manual. 7th ed: Springer; 2009.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Marianne M. Casilla-Lennon
    • 1
  • Patrick A. Kenney
    • 2
  • Matthew Wszolek
    • 3
  • John A. Libertino
    • 4
    • 5
  1. 1.Department of UrologyYale New Haven HealthNew HavenUSA
  2. 2.Department of Urology/Yale School of MedicineYale New Haven HospitalNew HavenUSA
  3. 3.Department of UrologyMassachusetts General HospitalBostonUSA
  4. 4.Tufts University School of MedicineBostonUSA
  5. 5.Department of UrologyMGH Cancer Center, Emerson HospitalConcordUSA

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