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Functional Outcomes Following Critical Illness

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Post-Intensive Care Syndrome

Part of the book series: Lessons from the ICU ((LEICU))

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Abstract

Improvements in critical care have led to reduced mortality but paradoxically may have promoted survival with increased morbidity. A myriad of functional disabilities range from impairment in lung function, to physical weakness and muscle dysfunction, to a wide range of neuropsychological morbidities, impairment in health-related quality of life, and inability to return to work. Moreover, caregivers, family, and close friends experience burden that may exceed their personal psychological resources. This results in medical complexity that may extend beyond a restrictive syndromic definition. The incremental knowledge contributed by the outcome literature over the past four decades has been limited by the marked heterogeneity in the approach to measuring outcomes. In this chapter, we will review the scope of this issue, assess the historic evolution of outcome measures, and identify factors that influence functional disability after critical illness. Finally, we will explore candidate multidimensional outcome measures for future outcomes and intervention studies designed to deliver risk-stratified, focused, and tailored patient-oriented care.

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Author information

Authors and Affiliations

  1. Adult Critical Care Medicine Fellowship Program, University of Toronto, Toronto, ON, Canada

    Abdulrahman A. Al-Fares

  2. Al-Amiri Hospital, Ministry of Health, Kuwait City, Kuwait

    Abdulrahman A. Al-Fares

  3. Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada

    Abdulrahman A. Al-Fares & Margaret Herridge

  4. Toronto General Hospital, Toronto, ON, Canada

    Abdulrahman A. Al-Fares

  5. Respiratory and CCM, Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Margaret Herridge

  6. Toronto General Research Institute, University of Toronto, Toronto, ON, Canada

    Margaret Herridge

  7. Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada

    Margaret Herridge

Authors
  1. Abdulrahman A. Al-Fares
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  2. Margaret Herridge
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Correspondence to Abdulrahman A. Al-Fares .

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Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium

    Jean-Charles Preiser

  2. Respiratory and CCM, Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Margaret Herridge

  3. Medical Intensive Care Unit, AP-HP Saint-Louis Hospital, Paris, France

    Elie Azoulay

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Al-Fares, A.A., Herridge, M. (2020). Functional Outcomes Following Critical Illness. In: Preiser, JC., Herridge, M., Azoulay, E. (eds) Post-Intensive Care Syndrome. Lessons from the ICU. Springer, Cham. https://doi.org/10.1007/978-3-030-24250-3_6

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